Hypoxia Conditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Induce Increased Vascular Tube Formation in vitro

Hypoxia Conditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Induce Increased Vascular Tube Formation in vitro

Mesenchymal stem/stromal cells (MSCs) display a variety of therapeutically relevant effects, such as the induction of angiogenesis, particularly under hypoxic conditions. It is generally recognized that MSCs exert their effects by secretion of paracrine factors and by stimulation of host cells. Furt...

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Bibliographic Details
Main Authors: Ciarra Almeria, René Weiss, Michelle Roy, Carla Tripisciano, Cornelia Kasper, Viktoria Weber, Dominik Egger
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mesenchymal stem cells
extracellular vesicles
hypoxia
angiogenesis
tube formation
therapeutic potential
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00292/full

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