Comparing the Primary and Recall Immune Response Induced by a New EV71 Vaccine Using Systems Biology Approaches.
Three inactivated EV71 whole-virus vaccines have completed Phase III clinical trials in mainland China, with high efficacy, satisfactory safety, and sustained immunogenicity. However, the molecular mechanisms how this new vaccine elicit potent immune response remain poorly understood. To characteriz...
Main Authors: | Jie Shao, Junnan Zhang, Xing Wu, Qunying Mao, Pan Chen, Fengcai Zhu, Miao Xu, Wei Kong, Zhenglun Liang, Junzhi Wang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4605509?pdf=render |
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