Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India
Introduction: Mature Cystic Teratoma (MCT) is the most common benign neoplasm of the ovary constituting 10-20% of all the ovarian tumours. Although, much has been published about ovarian teratomas, in English literature, there are very few retrospective cross sectional studies from India to unde...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/9612/23909_CE[Ra1]_F(RK)_PF1(SH_RK)_PFA(P)_PF2(SG_SS).pdf |
| Summary: | Introduction: Mature Cystic Teratoma (MCT) is the most
common benign neoplasm of the ovary constituting 10-20% of
all the ovarian tumours. Although, much has been published
about ovarian teratomas, in English literature, there are very few
retrospective cross sectional studies from India to understand
the epidemiology of the disease.
Aim: To evaluate the prevalence, clinicopathological characteristics
and complications of MCT of the ovary.
Materials and Methods: This was a retrospective study of 223
cases of MCT of ovary received over a period of 25 years from
1990 to 2014. The data regarding age, size, laterality, gross,
morphological features, complications and surgery performed
was retrieved from the archives of pathology department.
Descriptive statistics was performed using SPSS software
version 22 and the results were expressed as percentages.
Results: MCT constituted 20.2% of the total ovarian neoplasms
and 78.5% of all the germ cell tumours. The mean age of the
patients with MCT was 32.5±13.11 years and the mean size
of tumour was 8.6±3.1 cm. Torsion was the most common
complication of these tumours. Malignant transformation of this
tumour though rare was seen in 3.5% of the cases.
Conclusion: MCT are most common tumours of the ovary.
Though predominantly seen in reproductive age group, they may
also be seen in children and postmenopausal women. Torsion is
the most common complication of this tumour. Age of the patient
and the size of the tumour are important prognostic factors in
terms of malignant transformation of teratomas. Since 8.9% of
these tumours were bilateral it is essential to thoroughly examine
the contralateral ovary to rule out bilaterality. Early diagnosis and
early treatment is essential to preserve fertility in these patients. |
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| ISSN: | 2249-782X 0973-709X |