Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India
Introduction: Mature Cystic Teratoma (MCT) is the most common benign neoplasm of the ovary constituting 10-20% of all the ovarian tumours. Although, much has been published about ovarian teratomas, in English literature, there are very few retrospective cross sectional studies from India to unde...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-04-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/9612/23909_CE[Ra1]_F(RK)_PF1(SH_RK)_PFA(P)_PF2(SG_SS).pdf |
| _version_ | 1818777677927022592 |
|---|---|
| author | Ruchi Rathore Sonal Sharma Deepshikha Arora |
| author_facet | Ruchi Rathore Sonal Sharma Deepshikha Arora |
| author_sort | Ruchi Rathore |
| collection | DOAJ |
| description | Introduction: Mature Cystic Teratoma (MCT) is the most
common benign neoplasm of the ovary constituting 10-20% of
all the ovarian tumours. Although, much has been published
about ovarian teratomas, in English literature, there are very few
retrospective cross sectional studies from India to understand
the epidemiology of the disease.
Aim: To evaluate the prevalence, clinicopathological characteristics
and complications of MCT of the ovary.
Materials and Methods: This was a retrospective study of 223
cases of MCT of ovary received over a period of 25 years from
1990 to 2014. The data regarding age, size, laterality, gross,
morphological features, complications and surgery performed
was retrieved from the archives of pathology department.
Descriptive statistics was performed using SPSS software
version 22 and the results were expressed as percentages.
Results: MCT constituted 20.2% of the total ovarian neoplasms
and 78.5% of all the germ cell tumours. The mean age of the
patients with MCT was 32.5±13.11 years and the mean size
of tumour was 8.6±3.1 cm. Torsion was the most common
complication of these tumours. Malignant transformation of this
tumour though rare was seen in 3.5% of the cases.
Conclusion: MCT are most common tumours of the ovary.
Though predominantly seen in reproductive age group, they may
also be seen in children and postmenopausal women. Torsion is
the most common complication of this tumour. Age of the patient
and the size of the tumour are important prognostic factors in
terms of malignant transformation of teratomas. Since 8.9% of
these tumours were bilateral it is essential to thoroughly examine
the contralateral ovary to rule out bilaterality. Early diagnosis and
early treatment is essential to preserve fertility in these patients. |
| first_indexed | 2024-12-18T11:32:38Z |
| format | Article |
| id | doaj.art-6c45327f6cdd481aaafea6e5644f65bb |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-18T11:32:38Z |
| publishDate | 2017-04-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-6c45327f6cdd481aaafea6e5644f65bb2022-12-21T21:09:34ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-04-01114EC11EC1410.7860/JCDR/2017/23909.9612Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in IndiaRuchi Rathore0Sonal Sharma1Deepshikha Arora2Ex Senior Resident UCMS, Department of Pathology, Currently Assistant Professor, North Delhi Municipal Corporation Medical College, New Delhi, India.Director and Professor, Department of Pathology, University College of Medical Sciences, Dilshad Garden, New Delhi, India.Ex Junior Resident UCMS, Department of Pathology, Currently Medical Officer, CGHS, University College of Medical Sciences, Dilshad Garden, New Delhi, India.Introduction: Mature Cystic Teratoma (MCT) is the most common benign neoplasm of the ovary constituting 10-20% of all the ovarian tumours. Although, much has been published about ovarian teratomas, in English literature, there are very few retrospective cross sectional studies from India to understand the epidemiology of the disease. Aim: To evaluate the prevalence, clinicopathological characteristics and complications of MCT of the ovary. Materials and Methods: This was a retrospective study of 223 cases of MCT of ovary received over a period of 25 years from 1990 to 2014. The data regarding age, size, laterality, gross, morphological features, complications and surgery performed was retrieved from the archives of pathology department. Descriptive statistics was performed using SPSS software version 22 and the results were expressed as percentages. Results: MCT constituted 20.2% of the total ovarian neoplasms and 78.5% of all the germ cell tumours. The mean age of the patients with MCT was 32.5±13.11 years and the mean size of tumour was 8.6±3.1 cm. Torsion was the most common complication of these tumours. Malignant transformation of this tumour though rare was seen in 3.5% of the cases. Conclusion: MCT are most common tumours of the ovary. Though predominantly seen in reproductive age group, they may also be seen in children and postmenopausal women. Torsion is the most common complication of this tumour. Age of the patient and the size of the tumour are important prognostic factors in terms of malignant transformation of teratomas. Since 8.9% of these tumours were bilateral it is essential to thoroughly examine the contralateral ovary to rule out bilaterality. Early diagnosis and early treatment is essential to preserve fertility in these patients.https://jcdr.net/articles/PDF/9612/23909_CE[Ra1]_F(RK)_PF1(SH_RK)_PFA(P)_PF2(SG_SS).pdfgerm cell tumoursmalignant transformationovarian neoplasms |
| spellingShingle | Ruchi Rathore Sonal Sharma Deepshikha Arora Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India Journal of Clinical and Diagnostic Research germ cell tumours malignant transformation ovarian neoplasms |
| title | Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India |
| title_full | Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India |
| title_fullStr | Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India |
| title_full_unstemmed | Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India |
| title_short | Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India |
| title_sort | clinicopathological evaluation of 223 cases of mature cystic teratoma ovary 25 year experience in a single tertiary care centre in india |
| topic | germ cell tumours malignant transformation ovarian neoplasms |
| url | https://jcdr.net/articles/PDF/9612/23909_CE[Ra1]_F(RK)_PF1(SH_RK)_PFA(P)_PF2(SG_SS).pdf |
| work_keys_str_mv | AT ruchirathore clinicopathologicalevaluationof223casesofmaturecysticteratomaovary25yearexperienceinasingletertiarycarecentreinindia AT sonalsharma clinicopathologicalevaluationof223casesofmaturecysticteratomaovary25yearexperienceinasingletertiarycarecentreinindia AT deepshikhaarora clinicopathologicalevaluationof223casesofmaturecysticteratomaovary25yearexperienceinasingletertiarycarecentreinindia |