Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors

Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors

A series of new 1,3-diaryltriazene sulfonamides was synthesised by reaction of diazonium salt of metanilamide (3-aminobenzene sulfonamide) with substituted aromatic amines. The obtained new compounds were assayed as inhibitors of four physiologically and pharmacologically relevant human (h) isoforms...

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Bibliographic Details
Main Authors:	Suleyman Akocak, Nabih Lolak, Silvia Bua, Claudiu T. Supuran
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2018-01-01
Series:	Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:	Carbonic anhydrase inhibitors triazene isozymes metanilamide
Online Access:	http://dx.doi.org/10.1080/14756366.2018.1515933

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