Effects of subtotal pancreatectomy and long‐term glucose and lipid overload on insulin secretion and glucose homeostasis in minipigs

Effects of subtotal pancreatectomy and long‐term glucose and lipid overload on insulin secretion and glucose homeostasis in minipigs

Abstract Introduction Nowadays, there are no strong diabetic pig models, yet they are required for various types of diabetes research. Using cutting‐edge techniques, we attempted to develop a type 2 diabetic minipig model in this study by combining a partial pancreatectomy (Px) with an energetic ove...

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Bibliografiske detaljer
Main Authors: Rébecca Goutchtat, Audrey Quenon, Manon Clarisse, Nathalie Delalleau, Anaïs Coddeville, Mathilde Gobert, Valéry Gmyr, Julie Kerr‐Conte, François Pattou, Thomas Hubert
Format: Article
Sprog:English
Udgivet: Wiley 2023-07-01
Serier:Endocrinology, Diabetes & Metabolism
Fag:
energetic overload
hyperglycemia
minipig model
pancreatectomy
type 2 diabetes
Online adgang:https://doi.org/10.1002/edm2.425

Internet

https://doi.org/10.1002/edm2.425

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