Crosstalk between glioblastoma and tumor microenvironment drives proneural–mesenchymal transition through ligand-receptor interactions

Crosstalk between glioblastoma and tumor microenvironment drives proneural–mesenchymal transition through ligand-receptor interactions

Glioblastoma (GBM) is the most common intrinsic and aggressive primary brain tumor in adults, with a median survival of approximately 15 months. GBM heterogeneity is considered responsible for the treatment resistance and unfavorable prognosis. Proneural-mesenchymal transition (PMT) represents GBM m...

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Bibliographic Details
Main Authors: Yancheng Lai, Xiaole Lu, Yankai Liao, Pei Ouyang, Hai Wang, Xian Zhang, Guanglong Huang, Songtao Qi, Yaomin Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Genes and Diseases
Subjects:
Autocrine
Glioblastoma
Ligand-receptor interaction
Microenvironment
Paracrine
Proneural-mesenchymal transition
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223003252

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http://www.sciencedirect.com/science/article/pii/S2352304223003252

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