Treatment satisfaction of patients with psoriasis with topical therapy in a real-world setting: unmet need for higher effectiveness

Background Topical medication is the mainstay for treatment of mild psoriasis. However, dissatisfaction with topicals is common and rates of non-adherence are high. Assessing patients’ perspectives can help to identify unmet needs. Objective Our aim was to investigate satisfaction of patients with p...

Full description

Bibliographic Details
Main Authors: Nadia Ninosu, Suna Hoelker, Max Kappenstein, Sylvia Buettner, Wiebke K. Peitsch, Marthe-Lisa Schaarschmidt
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2023.2200570
_version_ 1827816483399401472
author Nadia Ninosu
Suna Hoelker
Max Kappenstein
Sylvia Buettner
Wiebke K. Peitsch
Marthe-Lisa Schaarschmidt
author_facet Nadia Ninosu
Suna Hoelker
Max Kappenstein
Sylvia Buettner
Wiebke K. Peitsch
Marthe-Lisa Schaarschmidt
author_sort Nadia Ninosu
collection DOAJ
description Background Topical medication is the mainstay for treatment of mild psoriasis. However, dissatisfaction with topicals is common and rates of non-adherence are high. Assessing patients’ perspectives can help to identify unmet needs. Objective Our aim was to investigate satisfaction of patients with psoriasis with topical therapy and to determine influencing factors. Methods Patients were recruited from the Department of Dermatology, University Medical Center Mannheim, Germany. Satisfaction was assessed using the Treatment Satisfaction Questionnaire for Medication version 1.4 with the domains effectiveness, side effects, convenience, and global satisfaction (scale 0–100 each). The impact of sociodemographic and disease characteristics was determined by multivariate regression. Results Averaged across the cohort (n = 122, mean age 52.5 years, 58.2% male), the side effects domain had the highest mean satisfaction score (89.7), followed by convenience (72.5), global satisfaction (60.8), and effectiveness (55.0). Comparing specific medications, combinations of corticosteroids and vitamin D analogues were rated best in effectiveness. Treatment satisfaction was influenced by age, partnership, ability to apply topicals independently, disease-related quality-of-life impairment, sole or adjunctive use of topicals and pruritus. Conclusions Participants were particularly satisfied with safety but rather dissatisfied with effectiveness of topicals. Topical therapy should be adapted to individual needs with special attention to effectiveness.
first_indexed 2024-03-12T00:14:56Z
format Article
id doaj.art-6c4ac45bd451403da08b3644597e52a1
institution Directory Open Access Journal
issn 0954-6634
1471-1753
language English
last_indexed 2024-03-12T00:14:56Z
publishDate 2023-12-01
publisher Taylor & Francis Group
record_format Article
series Journal of Dermatological Treatment
spelling doaj.art-6c4ac45bd451403da08b3644597e52a12023-09-15T14:28:53ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532023-12-0134110.1080/09546634.2023.22005702200570Treatment satisfaction of patients with psoriasis with topical therapy in a real-world setting: unmet need for higher effectivenessNadia Ninosu0Suna Hoelker1Max Kappenstein2Sylvia Buettner3Wiebke K. Peitsch4Marthe-Lisa Schaarschmidt5Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Heidelberg UniversityDepartment of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Heidelberg UniversityDepartment of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Heidelberg UniversityDepartment of Biomathematics and Medical Statistics, Faculty of Medicine Mannheim, University of HeidelbergDepartment of Dermatology and Phlebology, Vivantes Klinikum im FriedrichshainDepartment of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Heidelberg UniversityBackground Topical medication is the mainstay for treatment of mild psoriasis. However, dissatisfaction with topicals is common and rates of non-adherence are high. Assessing patients’ perspectives can help to identify unmet needs. Objective Our aim was to investigate satisfaction of patients with psoriasis with topical therapy and to determine influencing factors. Methods Patients were recruited from the Department of Dermatology, University Medical Center Mannheim, Germany. Satisfaction was assessed using the Treatment Satisfaction Questionnaire for Medication version 1.4 with the domains effectiveness, side effects, convenience, and global satisfaction (scale 0–100 each). The impact of sociodemographic and disease characteristics was determined by multivariate regression. Results Averaged across the cohort (n = 122, mean age 52.5 years, 58.2% male), the side effects domain had the highest mean satisfaction score (89.7), followed by convenience (72.5), global satisfaction (60.8), and effectiveness (55.0). Comparing specific medications, combinations of corticosteroids and vitamin D analogues were rated best in effectiveness. Treatment satisfaction was influenced by age, partnership, ability to apply topicals independently, disease-related quality-of-life impairment, sole or adjunctive use of topicals and pruritus. Conclusions Participants were particularly satisfied with safety but rather dissatisfied with effectiveness of topicals. Topical therapy should be adapted to individual needs with special attention to effectiveness.http://dx.doi.org/10.1080/09546634.2023.2200570satisfactionpsoriasistopical therapytsqm
spellingShingle Nadia Ninosu
Suna Hoelker
Max Kappenstein
Sylvia Buettner
Wiebke K. Peitsch
Marthe-Lisa Schaarschmidt
Treatment satisfaction of patients with psoriasis with topical therapy in a real-world setting: unmet need for higher effectiveness
Journal of Dermatological Treatment
satisfaction
psoriasis
topical therapy
tsqm
title Treatment satisfaction of patients with psoriasis with topical therapy in a real-world setting: unmet need for higher effectiveness
title_full Treatment satisfaction of patients with psoriasis with topical therapy in a real-world setting: unmet need for higher effectiveness
title_fullStr Treatment satisfaction of patients with psoriasis with topical therapy in a real-world setting: unmet need for higher effectiveness
title_full_unstemmed Treatment satisfaction of patients with psoriasis with topical therapy in a real-world setting: unmet need for higher effectiveness
title_short Treatment satisfaction of patients with psoriasis with topical therapy in a real-world setting: unmet need for higher effectiveness
title_sort treatment satisfaction of patients with psoriasis with topical therapy in a real world setting unmet need for higher effectiveness
topic satisfaction
psoriasis
topical therapy
tsqm
url http://dx.doi.org/10.1080/09546634.2023.2200570
work_keys_str_mv AT nadianinosu treatmentsatisfactionofpatientswithpsoriasiswithtopicaltherapyinarealworldsettingunmetneedforhighereffectiveness
AT sunahoelker treatmentsatisfactionofpatientswithpsoriasiswithtopicaltherapyinarealworldsettingunmetneedforhighereffectiveness
AT maxkappenstein treatmentsatisfactionofpatientswithpsoriasiswithtopicaltherapyinarealworldsettingunmetneedforhighereffectiveness
AT sylviabuettner treatmentsatisfactionofpatientswithpsoriasiswithtopicaltherapyinarealworldsettingunmetneedforhighereffectiveness
AT wiebkekpeitsch treatmentsatisfactionofpatientswithpsoriasiswithtopicaltherapyinarealworldsettingunmetneedforhighereffectiveness
AT marthelisaschaarschmidt treatmentsatisfactionofpatientswithpsoriasiswithtopicaltherapyinarealworldsettingunmetneedforhighereffectiveness