Defining the Genes Required for Survival of Mycobacterium bovis in the Bovine Host Offers Novel Insights into the Genetic Basis of Survival of Pathogenic Mycobacteria

Defining the Genes Required for Survival of Mycobacterium bovis in the Bovine Host Offers Novel Insights into the Genetic Basis of Survival of Pathogenic Mycobacteria

ABSTRACT Tuberculosis has severe impacts on both humans and animals. Understanding the genetic basis of survival of both Mycobacterium tuberculosis, the human-adapted species, and Mycobacterium bovis, the animal-adapted species, is crucial to deciphering the biology of both pathogens. There are seve...

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Bibliographic Details
Main Authors: Amanda J. Gibson, Jennifer Stiens, Ian J. Passmore, Valwynne Faulkner, Josephous Miculob, Sam Willcocks, Michael Coad, Stefan Berg, Dirk Werling, Brendan W. Wren, Irene Nobeli, Bernardo Villarreal-Ramos, Sharon L. Kendall
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:mBio
Subjects:
Tn-seq
gene essentiality
One Health
tuberculosis
virulence factors
Online Access:https://journals.asm.org/doi/10.1128/mbio.00672-22

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