Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010

Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains. Data suggest that the widespread use of this monovalent rotavi...

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Main Authors: Tatiana Lundgren Rose, Marcelle Figueira Marques da Silva, Mariela Martinéz Goméz, Hugo Reis Resque, Maria Yury Travassos Ichihara, Eduardo de Mello Volotão, José Paulo Gagliardi Leite
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2013-11-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/19/11/12-1407_article
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author Tatiana Lundgren Rose
Marcelle Figueira Marques da Silva
Mariela Martinéz Goméz
Hugo Reis Resque
Maria Yury Travassos Ichihara
Eduardo de Mello Volotão
José Paulo Gagliardi Leite
author_facet Tatiana Lundgren Rose
Marcelle Figueira Marques da Silva
Mariela Martinéz Goméz
Hugo Reis Resque
Maria Yury Travassos Ichihara
Eduardo de Mello Volotão
José Paulo Gagliardi Leite
author_sort Tatiana Lundgren Rose
collection DOAJ
description Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains. Data suggest that the widespread use of this monovalent rotavirus vaccine may introduce vaccine genes into circulating human rotaviruses or vice versa.
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spelling doaj.art-6c4f0dd78c6d4592ab811411fff90ed92022-12-22T03:06:02ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592013-11-0119111843184610.3201/eid1911.121407Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010Tatiana Lundgren RoseMarcelle Figueira Marques da SilvaMariela Martinéz GomézHugo Reis ResqueMaria Yury Travassos IchiharaEduardo de Mello VolotãoJosé Paulo Gagliardi LeiteAnalysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains. Data suggest that the widespread use of this monovalent rotavirus vaccine may introduce vaccine genes into circulating human rotaviruses or vice versa.https://wwwnc.cdc.gov/eid/article/19/11/12-1407_articleRotarixvaccineG1P[8] strainsphylogenetic analysisreassortmentrotavirus
spellingShingle Tatiana Lundgren Rose
Marcelle Figueira Marques da Silva
Mariela Martinéz Goméz
Hugo Reis Resque
Maria Yury Travassos Ichihara
Eduardo de Mello Volotão
José Paulo Gagliardi Leite
Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010
Emerging Infectious Diseases
Rotarix
vaccine
G1P[8] strains
phylogenetic analysis
reassortment
rotavirus
title Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010
title_full Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010
title_fullStr Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010
title_full_unstemmed Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010
title_short Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010
title_sort evidence of vaccine related reassortment of rotavirus brazil 2008 2010
topic Rotarix
vaccine
G1P[8] strains
phylogenetic analysis
reassortment
rotavirus
url https://wwwnc.cdc.gov/eid/article/19/11/12-1407_article
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