Long-term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult Chinese
ObjectiveThis study aims to investigate the relationship between exposure to air pollution and adverse meteorological factors, and the risk of osteoporosis.MethodsWe diagnosed osteoporosis by assessing bone mineral density through Dual-Energy X-ray absorptiometry in 2,361 participants from Jiangsu,...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1361911/full |
| _version_ | 1797341216355909632 |
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| author | Hong Sun Yanan Wan Xiaoqun Pan Wanxi You Jianxin Shen Junhua Lu Gangfeng Zheng Xinlin Li Xiaoxi Xing Yongqing Zhang |
| author_facet | Hong Sun Yanan Wan Xiaoqun Pan Wanxi You Jianxin Shen Junhua Lu Gangfeng Zheng Xinlin Li Xiaoxi Xing Yongqing Zhang |
| author_sort | Hong Sun |
| collection | DOAJ |
| description | ObjectiveThis study aims to investigate the relationship between exposure to air pollution and adverse meteorological factors, and the risk of osteoporosis.MethodsWe diagnosed osteoporosis by assessing bone mineral density through Dual-Energy X-ray absorptiometry in 2,361 participants from Jiangsu, China. Additionally, we conducted physical examinations, blood tests, and questionnaires. We evaluated pollution exposure levels using grid data, considering various lag periods (ranging from one to five years) based on participants’ addresses. We utilized logistic regression analysis, adjusted for temperature, humidity, and individual factors, to examine the connections between osteoporosis and seven air pollutants: PM₁, PM₂.₅, PM₁₀, SO₂, NO₂, CO, and O₃. We assessed the robustness of our study through two-pollutant models and distributed lag non-linear models (DLNM) and explored susceptibility using stratified analyses.ResultsIn Jiangsu, China, the prevalence of osteoporosis among individuals aged 40 and above was found to be 15.1%. A consistent association was observed between osteoporosis and the five-year average exposure to most pollutants, including PM₂.₅, PM₁₀, CO, and O₃. The effects of PM₁₀ and CO remained stable even after adjusting for the presence of a second pollutant. However, the levels of PM₁ and PM₂.₅ were significantly influenced by O₃ levels. Individuals aged 60 and above, those with a BMI of 25 or higher, and males were found to be more susceptible to the effects of air pollution. Interestingly, males showed a significantly higher susceptibility to PM₁ and PM₂.₅ compared to females. This study provides valuable insights into the long-term effects of air pollution on osteoporosis risk among the adult population in China.ConclusionThis study indicates a potential association between air pollutants and osteoporosis, particularly with long-term exposure. The risk of osteoporosis induced by air pollution is found to be higher in individuals aged 60 and above, those with a BMI greater than 25, and males. These findings underscore the need for further research and public health interventions to mitigate the impact of air pollution on bone health. |
| first_indexed | 2024-03-08T10:15:40Z |
| format | Article |
| id | doaj.art-6c510272234347d6a390324c8d660d6d |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-03-08T10:15:40Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-6c510272234347d6a390324c8d660d6d2024-01-29T04:15:29ZengFrontiers Media S.A.Frontiers in Public Health2296-25652024-01-011210.3389/fpubh.2024.13619111361911Long-term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult ChineseHong Sun0Yanan Wan1Xiaoqun Pan2Wanxi You3Jianxin Shen4Junhua Lu5Gangfeng Zheng6Xinlin Li7Xiaoxi Xing8Yongqing Zhang9Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, ChinaJiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, ChinaJiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, ChinaLuhe District Center for Disease Control and Prevention, Nanjing, Jiangsu, ChinaWujiang District Center for Disease Control and Prevention, Suzhou, Jiangsu, ChinaChongchuan District Center for Disease Control and Prevention, Nantong, Jiangsu, ChinaJingjiang Center for Disease Control and Prevention, Taizhou, Jiangsu, ChinaNantong Center for Disease Control and Prevention, Nantong, Jiangsu, ChinaQuanshan District Center for Disease Control and Prevention, Xuzhou, Jiangsu, ChinaJiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, ChinaObjectiveThis study aims to investigate the relationship between exposure to air pollution and adverse meteorological factors, and the risk of osteoporosis.MethodsWe diagnosed osteoporosis by assessing bone mineral density through Dual-Energy X-ray absorptiometry in 2,361 participants from Jiangsu, China. Additionally, we conducted physical examinations, blood tests, and questionnaires. We evaluated pollution exposure levels using grid data, considering various lag periods (ranging from one to five years) based on participants’ addresses. We utilized logistic regression analysis, adjusted for temperature, humidity, and individual factors, to examine the connections between osteoporosis and seven air pollutants: PM₁, PM₂.₅, PM₁₀, SO₂, NO₂, CO, and O₃. We assessed the robustness of our study through two-pollutant models and distributed lag non-linear models (DLNM) and explored susceptibility using stratified analyses.ResultsIn Jiangsu, China, the prevalence of osteoporosis among individuals aged 40 and above was found to be 15.1%. A consistent association was observed between osteoporosis and the five-year average exposure to most pollutants, including PM₂.₅, PM₁₀, CO, and O₃. The effects of PM₁₀ and CO remained stable even after adjusting for the presence of a second pollutant. However, the levels of PM₁ and PM₂.₅ were significantly influenced by O₃ levels. Individuals aged 60 and above, those with a BMI of 25 or higher, and males were found to be more susceptible to the effects of air pollution. Interestingly, males showed a significantly higher susceptibility to PM₁ and PM₂.₅ compared to females. This study provides valuable insights into the long-term effects of air pollution on osteoporosis risk among the adult population in China.ConclusionThis study indicates a potential association between air pollutants and osteoporosis, particularly with long-term exposure. The risk of osteoporosis induced by air pollution is found to be higher in individuals aged 60 and above, those with a BMI greater than 25, and males. These findings underscore the need for further research and public health interventions to mitigate the impact of air pollution on bone health.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1361911/fullbone mineral densityosteoporosis prevalenceparticulate matterlag timessusceptibility |
| spellingShingle | Hong Sun Yanan Wan Xiaoqun Pan Wanxi You Jianxin Shen Junhua Lu Gangfeng Zheng Xinlin Li Xiaoxi Xing Yongqing Zhang Long-term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult Chinese Frontiers in Public Health bone mineral density osteoporosis prevalence particulate matter lag times susceptibility |
| title | Long-term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult Chinese |
| title_full | Long-term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult Chinese |
| title_fullStr | Long-term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult Chinese |
| title_full_unstemmed | Long-term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult Chinese |
| title_short | Long-term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult Chinese |
| title_sort | long term air pollution and adverse meteorological factors might elevate the osteoporosis risk among adult chinese |
| topic | bone mineral density osteoporosis prevalence particulate matter lag times susceptibility |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1361911/full |
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