Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle
Aminoglycosides force read through of premature stop codon mutations and introduce new mutation-specific gene-corrective strategies in Duchenne muscular dystrophy. A chronic treatment with gentamicin (32 mg/kg/daily i.p., 8–12 weeks) was performed in exercised mdx mice with the dual aim to clarify t...
| Principais autores: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Elsevier
2008-11-01
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| coleção: | Neurobiology of Disease |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0969996108001575 |