Proliposomes: an approach for the development of stable liposome
Abstract Background: For several years, many attempts have been made for the improvement of liposomal stability. In 1986, Payne et al, introduced the concept of Pro-liposome for liposome preparation in order to avoid physicochemical instability encountered in some liposome suspensions such as aggre...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Facultad de Farmacia, Universidad de Granada
2020-03-01
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| Series: | Ars Pharmaceutica |
| Subjects: | |
| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942019000600231&tlng=en |
| _version_ | 1798033370143260672 |
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| author | Namita Singh Poonam Kushwaha Usama Ahmad Mohammad Abdullah |
| author_facet | Namita Singh Poonam Kushwaha Usama Ahmad Mohammad Abdullah |
| author_sort | Namita Singh |
| collection | DOAJ |
| description | Abstract Background: For several years, many attempts have been made for the improvement of liposomal stability. In 1986, Payne et al, introduced the concept of Pro-liposome for liposome preparation in order to avoid physicochemical instability encountered in some liposome suspensions such as aggregation, fusion, hydrolysis, and/or oxidation. Objective: The objective of this review is to focus on different aspects related to Proliposomes, their method of preparation, characterization techniques and pointing out its scope in drug delivery systems. Methods: Proliposomes are a new form of drug delivery systems. They are dry, free-flowing granular products composed of drug and phospholipid which, upon addition of water, disperse to form a multi-lamellar liposomal suspension. Results and Discussion: These Proliposomes are nearly as good as or perhaps better than conventional liposomes. In the present review attempt has been made to briefly explain the concept of Proliposomes with a focus on its components, preparation, characterizations and their field of application. Conclusion: Extensive survey of literatures and collected data suggests that Pro-liposomes are promising drug carriers for the future. |
| first_indexed | 2024-04-11T20:29:15Z |
| format | Article |
| id | doaj.art-6c534b830960478594d874b8436ed8cc |
| institution | Directory Open Access Journal |
| issn | 2340-9894 |
| language | English |
| last_indexed | 2024-04-11T20:29:15Z |
| publishDate | 2020-03-01 |
| publisher | Facultad de Farmacia, Universidad de Granada |
| record_format | Article |
| series | Ars Pharmaceutica |
| spelling | doaj.art-6c534b830960478594d874b8436ed8cc2022-12-22T04:04:34ZengFacultad de Farmacia, Universidad de GranadaArs Pharmaceutica2340-98942020-03-0160423124010.30827/ars.v60i4.8517Proliposomes: an approach for the development of stable liposomeNamita SinghPoonam KushwahaUsama AhmadMohammad AbdullahAbstract Background: For several years, many attempts have been made for the improvement of liposomal stability. In 1986, Payne et al, introduced the concept of Pro-liposome for liposome preparation in order to avoid physicochemical instability encountered in some liposome suspensions such as aggregation, fusion, hydrolysis, and/or oxidation. Objective: The objective of this review is to focus on different aspects related to Proliposomes, their method of preparation, characterization techniques and pointing out its scope in drug delivery systems. Methods: Proliposomes are a new form of drug delivery systems. They are dry, free-flowing granular products composed of drug and phospholipid which, upon addition of water, disperse to form a multi-lamellar liposomal suspension. Results and Discussion: These Proliposomes are nearly as good as or perhaps better than conventional liposomes. In the present review attempt has been made to briefly explain the concept of Proliposomes with a focus on its components, preparation, characterizations and their field of application. Conclusion: Extensive survey of literatures and collected data suggests that Pro-liposomes are promising drug carriers for the future.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942019000600231&tlng=enLiposomeProliposomeStabilityBioavailabilityPhospholipidCholesterol |
| spellingShingle | Namita Singh Poonam Kushwaha Usama Ahmad Mohammad Abdullah Proliposomes: an approach for the development of stable liposome Ars Pharmaceutica Liposome Proliposome Stability Bioavailability Phospholipid Cholesterol |
| title | Proliposomes: an approach for the development of stable liposome |
| title_full | Proliposomes: an approach for the development of stable liposome |
| title_fullStr | Proliposomes: an approach for the development of stable liposome |
| title_full_unstemmed | Proliposomes: an approach for the development of stable liposome |
| title_short | Proliposomes: an approach for the development of stable liposome |
| title_sort | proliposomes an approach for the development of stable liposome |
| topic | Liposome Proliposome Stability Bioavailability Phospholipid Cholesterol |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942019000600231&tlng=en |
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