Hybrid PET/MR Imaging and Brain Connectivity
In recent years, brain connectivity is gaining ever-increasing interest from the interdisciplinary research community. The study of brain connectivity is characterized by a multifaceted approach providing both structural and functional evidence of the relationship between cerebral regions at differe...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-03-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00064/full |
| _version_ | 1818057923330310144 |
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| author | Marco eAiello Carlo eCavaliere Marco eSalvatore |
| author_facet | Marco eAiello Carlo eCavaliere Marco eSalvatore |
| author_sort | Marco eAiello |
| collection | DOAJ |
| description | In recent years, brain connectivity is gaining ever-increasing interest from the interdisciplinary research community. The study of brain connectivity is characterized by a multifaceted approach providing both structural and functional evidence of the relationship between cerebral regions at different scales. Although magnetic resonance (MR) is the most established imaging modality for investigating connectivity in vivo, the recent advent of hybrid positron emission tomography (PET)/MR scanners paved the way for more comprehensive investigation of brain organization and physiology. Due to the high sensitivity and biochemical specificity of radiotracers, combining MR with PET imaging may enrich our ability to investigate connectivity by introducing the concept of metabolic connectivity and cometomics and promoting new insights on the physiological and molecular bases underlying high-level neural organization. This review aims to describe and summarize the main methods of analysis of brain connectivity employed in MR imaging and nuclear medicine. Moreover, it will discuss practical aspects and state-of-the-art techniques for exploiting hybrid PET/MR imaging to investigate the relationship of physiological processes and brain connectivity. |
| first_indexed | 2024-12-10T12:52:27Z |
| format | Article |
| id | doaj.art-6c53f888aaa64d1cbd06073fd77d1d4f |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-10T12:52:27Z |
| publishDate | 2016-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-6c53f888aaa64d1cbd06073fd77d1d4f2022-12-22T01:48:13ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2016-03-011010.3389/fnins.2016.00064174361Hybrid PET/MR Imaging and Brain ConnectivityMarco eAiello0Carlo eCavaliere1Marco eSalvatore2IRCCS SDNIRCCS SDNIRCCS SDNIn recent years, brain connectivity is gaining ever-increasing interest from the interdisciplinary research community. The study of brain connectivity is characterized by a multifaceted approach providing both structural and functional evidence of the relationship between cerebral regions at different scales. Although magnetic resonance (MR) is the most established imaging modality for investigating connectivity in vivo, the recent advent of hybrid positron emission tomography (PET)/MR scanners paved the way for more comprehensive investigation of brain organization and physiology. Due to the high sensitivity and biochemical specificity of radiotracers, combining MR with PET imaging may enrich our ability to investigate connectivity by introducing the concept of metabolic connectivity and cometomics and promoting new insights on the physiological and molecular bases underlying high-level neural organization. This review aims to describe and summarize the main methods of analysis of brain connectivity employed in MR imaging and nuclear medicine. Moreover, it will discuss practical aspects and state-of-the-art techniques for exploiting hybrid PET/MR imaging to investigate the relationship of physiological processes and brain connectivity.http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00064/fullfMRIPETMetabolic Networksresting stateconnectomeMR |
| spellingShingle | Marco eAiello Carlo eCavaliere Marco eSalvatore Hybrid PET/MR Imaging and Brain Connectivity Frontiers in Neuroscience fMRI PET Metabolic Networks resting state connectome MR |
| title | Hybrid PET/MR Imaging and Brain Connectivity |
| title_full | Hybrid PET/MR Imaging and Brain Connectivity |
| title_fullStr | Hybrid PET/MR Imaging and Brain Connectivity |
| title_full_unstemmed | Hybrid PET/MR Imaging and Brain Connectivity |
| title_short | Hybrid PET/MR Imaging and Brain Connectivity |
| title_sort | hybrid pet mr imaging and brain connectivity |
| topic | fMRI PET Metabolic Networks resting state connectome MR |
| url | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00064/full |
| work_keys_str_mv | AT marcoeaiello hybridpetmrimagingandbrainconnectivity AT carloecavaliere hybridpetmrimagingandbrainconnectivity AT marcoesalvatore hybridpetmrimagingandbrainconnectivity |