Utilizing 2D-region-based CNNs for automatic dendritic spine detection in 3D live cell imaging
Abstract Dendritic spines are considered a morphological proxy for excitatory synapses, rendering them a target of many different lines of research. Over recent years, it has become possible to simultaneously image large numbers of dendritic spines in 3D volumes of neural tissue. In contrast, curren...
Main Authors: | Fabian W. Vogel, Sercan Alipek, Jens-Bastian Eppler, Pamela Osuna-Vargas, Jochen Triesch, Diane Bissen, Amparo Acker-Palmer, Simon Rumpel, Matthias Kaschube |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-47070-3 |
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