A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C.

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C.

BACKGROUND:To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C. METHODOLOGY/PRINCIPAL FINDINGS:Associations between a functionally relevant polymorphism in the gene encoding the vitamin D 1α-hydroxyla...

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Main Authors: Christian M Lange, Stephanie Bibert, Zoltan Kutalik, Philippe Burgisser, Andreas Cerny, Jean-Francois Dufour, Andreas Geier, Tilman J Gerlach, Markus H Heim, Raffaele Malinverni, Francesco Negro, Stephan Regenass, Klaus Badenhoop, Jörg Bojunga, Christoph Sarrazin, Stefan Zeuzem, Tobias Müller, Thomas Berg, Pierre-Yves Bochud, Darius Moradpour, Swiss Hepatitis C Cohort Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3395683?pdf=render

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