Brain perfusion impairment in neurologically asymptomatic adult patients with Sickle-Cell Disease shown by voxel-based analysis of SPECT images

Brain perfusion impairment in neurologically asymptomatic adult patients with Sickle-Cell Disease shown by voxel-based analysis of SPECT images

Cerebrovascular lesions are frequently observed in patients with sickle cell disease (SCD) and these structural lesions are preceded by insidious perfusion deficits. Our aim was to investigate the presence of brain perfusion deficits in neurologically asymptomatic SCD patients, especially affecting...

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Bibliographic Details
Main Authors: Leonardo eDeus-Silva, Leonardo eBonilha, Benito Pereira Damasceno, Andre Luiz Costa, Clarissa Lin Yasuda, Fernando Ferreira Costa, Allan Oliveira Santos, Elba eEtchebehere, Regis eOquendo-Nogueira, Renata eFockink, Claudio Fróes de Freitas, Edwaldo Eduardo Camargo, Li Li Min, Fernando eCendes, Sara Ollala Saad
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Neurology
Subjects:
Image Processing, Computer-Assisted
Brain Perfusion
Sickle Cell Disease
SPECT
voxel based analysis.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00207/full

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