An atypical form of retinitis pigmentosa: A case report
Key Clinical Message This case contributes to the new knowledge of unilateral pericentral RP. Multimodal imaging provides valuable information to better understand the disease. The development is significantly slow and defines a better clinical course than typical RP. Pericentral RP presents with un...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-11-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.8221 |
| _version_ | 1797449699371778048 |
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| author | Yuanfeng Xue Bangtao Yao |
| author_facet | Yuanfeng Xue Bangtao Yao |
| author_sort | Yuanfeng Xue |
| collection | DOAJ |
| description | Key Clinical Message This case contributes to the new knowledge of unilateral pericentral RP. Multimodal imaging provides valuable information to better understand the disease. The development is significantly slow and defines a better clinical course than typical RP. Pericentral RP presents with unremarkable night blindness, which can be easily misdiagnosed by ophthalmologists. Abstract Unilateral pericentral retinitis pigmentosa (RP) is a rare, atypical, mild form of RP that affects the pericentral retina close to the vascular arcades and tends to spare the far‐peripheral retina in one eye, while the fellow eye remains completely unaffected. A 71‐year‐old Chinese woman presented with blurred vision in her right eye for several decades, however, her left eye was unaffected. Fundus photography revealed bone‐spicule pigmentation located at the pericentral retina of her right eye. Spectral‐domain optical coherence tomography revealed significant atrophy of the outer retina and retinal pigment epithelium, and an evident absence of the ellipsoid zone in the right eye. The visual field showed a wide‐range paracentral scotoma in the right eye. The full‐field electroretinogram demonstrated subnormal amplitudes of dark and light adaption in the right eye. No significant changes were observed during a further 5‐year follow‐up. Multimodal imaging provides valuable information to better understand unilateral pericentral RP. The development of unilateral pericentral RP is significantly slow and defines a better clinical course than the typical RP. Pericentral RP presents with slight visual reduction and unremarkable night blindness, which can be easily misdiagnosis by ophthalmologists. Reasonable prevention measures, screening methods, and timely diagnosis are beneficial for RP patients. |
| first_indexed | 2024-03-09T14:29:47Z |
| format | Article |
| id | doaj.art-6c560fb5d26b47758e52a2a2986d676e |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-09T14:29:47Z |
| publishDate | 2023-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-6c560fb5d26b47758e52a2a2986d676e2023-11-28T04:14:45ZengWileyClinical Case Reports2050-09042023-11-011111n/an/a10.1002/ccr3.8221An atypical form of retinitis pigmentosa: A case reportYuanfeng Xue0Bangtao Yao1Department of General Practice Nanjing Lishui District Baima Health Hospital Nanjing ChinaDepartment of Ophthalmology, Nanjing Lishui People's Hospital, Zhongda Hospital Lishui branch Southeast University Nanjing ChinaKey Clinical Message This case contributes to the new knowledge of unilateral pericentral RP. Multimodal imaging provides valuable information to better understand the disease. The development is significantly slow and defines a better clinical course than typical RP. Pericentral RP presents with unremarkable night blindness, which can be easily misdiagnosed by ophthalmologists. Abstract Unilateral pericentral retinitis pigmentosa (RP) is a rare, atypical, mild form of RP that affects the pericentral retina close to the vascular arcades and tends to spare the far‐peripheral retina in one eye, while the fellow eye remains completely unaffected. A 71‐year‐old Chinese woman presented with blurred vision in her right eye for several decades, however, her left eye was unaffected. Fundus photography revealed bone‐spicule pigmentation located at the pericentral retina of her right eye. Spectral‐domain optical coherence tomography revealed significant atrophy of the outer retina and retinal pigment epithelium, and an evident absence of the ellipsoid zone in the right eye. The visual field showed a wide‐range paracentral scotoma in the right eye. The full‐field electroretinogram demonstrated subnormal amplitudes of dark and light adaption in the right eye. No significant changes were observed during a further 5‐year follow‐up. Multimodal imaging provides valuable information to better understand unilateral pericentral RP. The development of unilateral pericentral RP is significantly slow and defines a better clinical course than the typical RP. Pericentral RP presents with slight visual reduction and unremarkable night blindness, which can be easily misdiagnosis by ophthalmologists. Reasonable prevention measures, screening methods, and timely diagnosis are beneficial for RP patients.https://doi.org/10.1002/ccr3.8221best‐corrected visual acuitycase reportfull‐field electroretinogrammultimodal imagingunilateral pericentral retinitis pigmentosa |
| spellingShingle | Yuanfeng Xue Bangtao Yao An atypical form of retinitis pigmentosa: A case report Clinical Case Reports best‐corrected visual acuity case report full‐field electroretinogram multimodal imaging unilateral pericentral retinitis pigmentosa |
| title | An atypical form of retinitis pigmentosa: A case report |
| title_full | An atypical form of retinitis pigmentosa: A case report |
| title_fullStr | An atypical form of retinitis pigmentosa: A case report |
| title_full_unstemmed | An atypical form of retinitis pigmentosa: A case report |
| title_short | An atypical form of retinitis pigmentosa: A case report |
| title_sort | atypical form of retinitis pigmentosa a case report |
| topic | best‐corrected visual acuity case report full‐field electroretinogram multimodal imaging unilateral pericentral retinitis pigmentosa |
| url | https://doi.org/10.1002/ccr3.8221 |
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