Longitudinal Evaluation of Serum MOG-IgG and AQP4-IgG Antibodies in NMOSD by a Semiquantitative Ratiometric Method

Longitudinal Evaluation of Serum MOG-IgG and AQP4-IgG Antibodies in NMOSD by a Semiquantitative Ratiometric Method

Background and purpose: Immunoadsorption (IA) is an antibody-depleting therapy used to treat neuromyelitis optica spectrum disorder (NMOSD) associated to antiaquaporin 4 (anti-AQP4-IgG) and antimyelin oligodendrocyte glycoprotein (anti-MOG-IgG) serum autoantibodies. Our aim was to evaluate longitudi...

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Bibliographic Details
Main Authors: Luca Bollo, Pietro Iaffaldano, Maddalena Ruggieri, Claudia Palazzo, Mariangela Mastrapasqua, Alessia Manni, Damiano Paolicelli, Antonio Frigeri, Maria Trojano
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neurology
Subjects:
NMO antibodies
NMOSD
NMO spectrum disorder
MOG (myelin oligodendrocyte glyco protein)
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.633115/full

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