Mojabanchromanol Isolated from <i>Sargassum horneri</i> Attenuates Particulate Matter Induced Inflammatory Responses via Suppressing TLR2/4/7-MAPK Signaling in MLE-12 Cells

Mojabanchromanol Isolated from <i>Sargassum horneri</i> Attenuates Particulate Matter Induced Inflammatory Responses via Suppressing TLR2/4/7-MAPK Signaling in MLE-12 Cells

Chromanols from marine algae are studied for drug development due to its prominent bioactive properties, and mojabanchromanol (MC), a chromanol isolated from a brown algae <i>Sargassum horneri</i>, is found to possess anti-oxidant potential. In this study, we hypothesized MC may attenuat...

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Bibliographic Details
Main Authors: Kalahe Hewage Iresha Nadeeka Madushani Herath, Hyo Jin Kim, Jae-Hyuk Jang, Hyun-Soo Kim, Hyun Jung Kim, You-Jin Jeon, Youngheun Jee
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Marine Drugs
Subjects:
Mojabanchromanol
TLR2/4/7
MAPK
IL-1β
IL-6
<i>Sargassum horneri</i>
Online Access:https://www.mdpi.com/1660-3397/18/7/355

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