Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated from Wild Birds (Mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea
Starting in late November 2010, the H5N1 highly pathogenic avian influenza (HPAI) virus was isolated from many types of wild ducks and raptors and was subsequently isolated from poultry in Korea. We assessed the genetic and pathogenic properties of the HPAI viruses isolated from a fecal sample from...
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-04-01
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| Series: | Viruses |
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| Online Access: | http://www.mdpi.com/1999-4915/5/4/1153 |
| _version_ | 1818684882089410560 |
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| author | Youn-Jeong Lee Jae-Hong Kim Hee-Soo Lee Kwang-Il Kim Byung Min Song Woo-Jin Jeon Kang-Seuk Choi Hyun-Mi Kang Jun-Gu Choi |
| author_facet | Youn-Jeong Lee Jae-Hong Kim Hee-Soo Lee Kwang-Il Kim Byung Min Song Woo-Jin Jeon Kang-Seuk Choi Hyun-Mi Kang Jun-Gu Choi |
| author_sort | Youn-Jeong Lee |
| collection | DOAJ |
| description | Starting in late November 2010, the H5N1 highly pathogenic avian influenza (HPAI) virus was isolated from many types of wild ducks and raptors and was subsequently isolated from poultry in Korea. We assessed the genetic and pathogenic properties of the HPAI viruses isolated from a fecal sample from a mandarin duck and a dead Eurasian eagle owl, the most affected wild bird species during the 2010/2011 HPAI outbreak in Korea. These viruses have similar genetic backgrounds and exhibited the highest genetic similarity with recent Eurasian clade 2.3.2.1 HPAI viruses. In animal inoculation experiments, regardless of their originating hosts, the two Korean isolates produced highly pathogenic characteristics in chickens, ducks and mice without pre-adaptation. These results raise concerns about veterinary and public health. Surveillance of wild birds could provide a good early warning signal for possible HPAI infection in poultry as well as in humans. |
| first_indexed | 2024-12-17T10:57:41Z |
| format | Article |
| id | doaj.art-6c5b704a0c2a42ce94c1b6e84b6430e8 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-12-17T10:57:41Z |
| publishDate | 2013-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-6c5b704a0c2a42ce94c1b6e84b6430e82022-12-21T21:51:46ZengMDPI AGViruses1999-49152013-04-01541153117410.3390/v5041153Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated from Wild Birds (Mandarin Duck and Eurasian Eagle Owl) in 2010 in KoreaYoun-Jeong LeeJae-Hong KimHee-Soo LeeKwang-Il KimByung Min SongWoo-Jin JeonKang-Seuk ChoiHyun-Mi KangJun-Gu ChoiStarting in late November 2010, the H5N1 highly pathogenic avian influenza (HPAI) virus was isolated from many types of wild ducks and raptors and was subsequently isolated from poultry in Korea. We assessed the genetic and pathogenic properties of the HPAI viruses isolated from a fecal sample from a mandarin duck and a dead Eurasian eagle owl, the most affected wild bird species during the 2010/2011 HPAI outbreak in Korea. These viruses have similar genetic backgrounds and exhibited the highest genetic similarity with recent Eurasian clade 2.3.2.1 HPAI viruses. In animal inoculation experiments, regardless of their originating hosts, the two Korean isolates produced highly pathogenic characteristics in chickens, ducks and mice without pre-adaptation. These results raise concerns about veterinary and public health. Surveillance of wild birds could provide a good early warning signal for possible HPAI infection in poultry as well as in humans.http://www.mdpi.com/1999-4915/5/4/1153H5N1highly pathogenic avian influenzaclade 2.3.2.1 |
| spellingShingle | Youn-Jeong Lee Jae-Hong Kim Hee-Soo Lee Kwang-Il Kim Byung Min Song Woo-Jin Jeon Kang-Seuk Choi Hyun-Mi Kang Jun-Gu Choi Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated from Wild Birds (Mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea Viruses H5N1 highly pathogenic avian influenza clade 2.3.2.1 |
| title | Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated from Wild Birds (Mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea |
| title_full | Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated from Wild Birds (Mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea |
| title_fullStr | Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated from Wild Birds (Mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea |
| title_full_unstemmed | Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated from Wild Birds (Mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea |
| title_short | Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated from Wild Birds (Mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea |
| title_sort | characterization of clade 2 3 2 1 h5n1 highly pathogenic avian influenza viruses isolated from wild birds mandarin duck and eurasian eagle owl in 2010 in korea |
| topic | H5N1 highly pathogenic avian influenza clade 2.3.2.1 |
| url | http://www.mdpi.com/1999-4915/5/4/1153 |
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