Halogenation of Pharmaceuticals Is an Impediment to Ready Biodegradability
For pharmacological reasons many active organic pharmaceutical substances (AOPSs) are singly or multiply halogenated. Halogenation can confer optimised steric fitting of an AOPS to its molecular receptor; moreover, by increasing the lipophilicity of a compound, passive permeation through bilipid mem...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
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| Series: | Water |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4441/15/13/2430 |