Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized with lesions of both upper and lower motor neurons. In accordance with modern diagnostics criteria, only clinical symptoms are used for revealing lesions of the upper motor neuron with the ALS, which often causes seriou...

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Main Authors: I. S. Bakulin, A. V. Chervyakov, M. N. Zakharova, N. A. Suponeva, M. A. Piradov
Format: Article
Language:Russian
Published: ABV-press 2015-06-01
Series:Нервно-мышечные болезни
Subjects:
Online Access:https://nmb.abvpress.ru/jour/article/view/115
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author I. S. Bakulin
A. V. Chervyakov
M. N. Zakharova
N. A. Suponeva
M. A. Piradov
author_facet I. S. Bakulin
A. V. Chervyakov
M. N. Zakharova
N. A. Suponeva
M. A. Piradov
author_sort I. S. Bakulin
collection DOAJ
description Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized with lesions of both upper and lower motor neurons. In accordance with modern diagnostics criteria, only clinical symptoms are used for revealing lesions of the upper motor neuron with the ALS, which often causes serious difficulties. Absence of the pyramidal syndrome does not allow diagnosing ALS, and the diagnosis of progressive muscular atrophy should be set in these cases. We describe a case of an isolated generalized lesion of the lower motor neuron with the signs of cortical motor neurons lesion revealed in the course of navigational transcranial magnetic stimulation. Possible reasons for difficulties in detecting pyramidal syndrome are discussed together with the necessity of working out the criteria of instrumental diagnostics of lesions of the upper motor neuron in ALS.
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spelling doaj.art-6c5d31cf5f114914b9b352ce2281aa6b2023-08-02T07:53:07ZrusABV-pressНервно-мышечные болезни2222-87212413-04432015-06-0152323710.17650/2222-8721-2015-5-2-32-37108Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case reportI. S. Bakulin0A. V. Chervyakov1M. N. Zakharova2N. A. Suponeva3M. A. Piradov4ФГБНУ «Научный центр неврологии»ФГБНУ «Научный центр неврологии»ФГБНУ «Научный центр неврологии»ФГБНУ «Научный центр неврологии»ФГБНУ «Научный центр неврологии»Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized with lesions of both upper and lower motor neurons. In accordance with modern diagnostics criteria, only clinical symptoms are used for revealing lesions of the upper motor neuron with the ALS, which often causes serious difficulties. Absence of the pyramidal syndrome does not allow diagnosing ALS, and the diagnosis of progressive muscular atrophy should be set in these cases. We describe a case of an isolated generalized lesion of the lower motor neuron with the signs of cortical motor neurons lesion revealed in the course of navigational transcranial magnetic stimulation. Possible reasons for difficulties in detecting pyramidal syndrome are discussed together with the necessity of working out the criteria of instrumental diagnostics of lesions of the upper motor neuron in ALS.https://nmb.abvpress.ru/jour/article/view/115боковой амиотрофический склерознавигационная транскраниальная магнитная стимуляцияпрогрессирующая мышечная атрофияболезнь двигательного нейронанейродегенерация
spellingShingle I. S. Bakulin
A. V. Chervyakov
M. N. Zakharova
N. A. Suponeva
M. A. Piradov
Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report
Нервно-мышечные болезни
боковой амиотрофический склероз
навигационная транскраниальная магнитная стимуляция
прогрессирующая мышечная атрофия
болезнь двигательного нейрона
нейродегенерация
title Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report
title_full Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report
title_fullStr Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report
title_full_unstemmed Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report
title_short Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report
title_sort navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions case report
topic боковой амиотрофический склероз
навигационная транскраниальная магнитная стимуляция
прогрессирующая мышечная атрофия
болезнь двигательного нейрона
нейродегенерация
url https://nmb.abvpress.ru/jour/article/view/115
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AT mnzakharova navigatedtranscranialmagneticstimulationpossibilitiesindifficultdiagnosticcasesuppermotorneuronlesionscasereport
AT nasuponeva navigatedtranscranialmagneticstimulationpossibilitiesindifficultdiagnosticcasesuppermotorneuronlesionscasereport
AT mapiradov navigatedtranscranialmagneticstimulationpossibilitiesindifficultdiagnosticcasesuppermotorneuronlesionscasereport