Regulation of hepatitis C virion production via phosphorylation of the NS5A protein.
Hepatitis C virus (HCV) is a significant pathogen, infecting some 170 million people worldwide. Persistent virus infection often leads to cirrhosis and liver cancer. In the infected cell many RNA directed processes must occur to maintain and spread infection. Viral genomic RNA is constantly replicat...
Main Authors: | Timothy L Tellinghuisen, Katie L Foss, Jason Treadaway |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-03-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2265800?pdf=render |
Similar Items
-
Akt Phosphorylation of Hepatitis C Virus NS5B Regulates Polymerase Activity and Hepatitis C Virus Infection
by: Rosario Sabariegos, et al.
Published: (2021-10-01) -
Phosphorylation of Serine 235 of the Hepatitis C Virus Non-Structural Protein NS5A by Multiple Kinases.
by: Kuan-Ying Lee, et al.
Published: (2016-01-01) -
Zika Virus NS2A-Mediated Virion Assembly
by: Xianwen Zhang, et al.
Published: (2019-10-01) -
The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A.
by: Simon Reiss, et al.
Published: (2013-05-01) -
NS5ATP9 Contributes to Inhibition of Cell Proliferation by Hepatitis C Virus (HCV) Nonstructural Protein 5A (NS5A) via MEK/Extracellular Signal Regulated Kinase (ERK) Pathway
by: Xuesong Gao, et al.
Published: (2013-05-01)