Characterization of oral lichen planus in a subset of patients: A single-center experience
Introduction: Lichen planus (LP) is a common chronic, mucocutaneous inflammatory disorder with unclear pathophysiology. The aim was to describe the epidemiology and clinicopathological characteristics of oral lichen planus (OLP) patients at King Abdulaziz University Dental Hospital (KAUDH) in Jeddah...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Saudi Journal of Oral Sciences |
| Subjects: | |
| Online Access: | http://www.saudijos.org//article.asp?issn=1658-6816;year=2020;volume=7;issue=3;spage=199;epage=205;aulast=Alhelo |
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| author | Azza F Alhelo Soulafa A Almazrooa Ghada A Mansour Sana A Alhamed Sara Alfarabi Sara K Akeel Nada O Binmadi Nada A Alhindi Lujain Alsulaimani Manal A Alamri Hani H Mawardi |
| author_facet | Azza F Alhelo Soulafa A Almazrooa Ghada A Mansour Sana A Alhamed Sara Alfarabi Sara K Akeel Nada O Binmadi Nada A Alhindi Lujain Alsulaimani Manal A Alamri Hani H Mawardi |
| author_sort | Azza F Alhelo |
| collection | DOAJ |
| description | Introduction: Lichen planus (LP) is a common chronic, mucocutaneous inflammatory disorder with unclear pathophysiology. The aim was to describe the epidemiology and clinicopathological characteristics of oral lichen planus (OLP) patients at King Abdulaziz University Dental Hospital (KAUDH) in Jeddah.
Materials and Methods: This was a retrospective, chart-review study which included OLP patients previously seen at KAUDH from June 2012 to June 2018. Demographic data, clinical features, management, and outcome were collected and analyzed. Diagnosis of LP was done using clinical criteria with or without histopathologic diagnosis, and the scoring system by Escudier et al. was used.
Results: Fifty patients with a mean age of 48 years (range: 21–71) and 2.5:1 female-to-male ratio were included in this study. The most concomitant systemic diseases were diabetes mellitus (30%) and hypertension (26%). Reticular OLP was the most common form (98%), followed by erythematous (66%), ulcerative (26%), and plaque-like type (8%). More than half of the patients were asymptomatic (64%), whereas twenty-two symptomatic patients were managed with either topical steroids, a combination of topical and systemic steroids, and/or intralesional steroid injections with 68% improvement.
Conclusion: Based on the current data, clinical features at KAUDH matched what has been previously reported in the literature. In addition, the response to different treatment modalities varied between patients which could be linked to factors such as disease extension and severity. |
| first_indexed | 2024-12-20T11:03:37Z |
| format | Article |
| id | doaj.art-6c5d9d6b71be4189a4e833c23d2cab97 |
| institution | Directory Open Access Journal |
| issn | 1658-6816 |
| language | English |
| last_indexed | 2024-12-20T11:03:37Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Oral Sciences |
| spelling | doaj.art-6c5d9d6b71be4189a4e833c23d2cab972022-12-21T19:42:57ZengWolters Kluwer Medknow PublicationsSaudi Journal of Oral Sciences1658-68162020-01-017319920510.4103/sjos.SJOralSci_11_20Characterization of oral lichen planus in a subset of patients: A single-center experienceAzza F AlheloSoulafa A AlmazrooaGhada A MansourSana A AlhamedSara AlfarabiSara K AkeelNada O BinmadiNada A AlhindiLujain AlsulaimaniManal A AlamriHani H MawardiIntroduction: Lichen planus (LP) is a common chronic, mucocutaneous inflammatory disorder with unclear pathophysiology. The aim was to describe the epidemiology and clinicopathological characteristics of oral lichen planus (OLP) patients at King Abdulaziz University Dental Hospital (KAUDH) in Jeddah. Materials and Methods: This was a retrospective, chart-review study which included OLP patients previously seen at KAUDH from June 2012 to June 2018. Demographic data, clinical features, management, and outcome were collected and analyzed. Diagnosis of LP was done using clinical criteria with or without histopathologic diagnosis, and the scoring system by Escudier et al. was used. Results: Fifty patients with a mean age of 48 years (range: 21–71) and 2.5:1 female-to-male ratio were included in this study. The most concomitant systemic diseases were diabetes mellitus (30%) and hypertension (26%). Reticular OLP was the most common form (98%), followed by erythematous (66%), ulcerative (26%), and plaque-like type (8%). More than half of the patients were asymptomatic (64%), whereas twenty-two symptomatic patients were managed with either topical steroids, a combination of topical and systemic steroids, and/or intralesional steroid injections with 68% improvement. Conclusion: Based on the current data, clinical features at KAUDH matched what has been previously reported in the literature. In addition, the response to different treatment modalities varied between patients which could be linked to factors such as disease extension and severity.http://www.saudijos.org//article.asp?issn=1658-6816;year=2020;volume=7;issue=3;spage=199;epage=205;aulast=Alhelolichen planuslichen planus characteristicslichen planus treatmentoral lichen planusoral ulcers |
| spellingShingle | Azza F Alhelo Soulafa A Almazrooa Ghada A Mansour Sana A Alhamed Sara Alfarabi Sara K Akeel Nada O Binmadi Nada A Alhindi Lujain Alsulaimani Manal A Alamri Hani H Mawardi Characterization of oral lichen planus in a subset of patients: A single-center experience Saudi Journal of Oral Sciences lichen planus lichen planus characteristics lichen planus treatment oral lichen planus oral ulcers |
| title | Characterization of oral lichen planus in a subset of patients: A single-center experience |
| title_full | Characterization of oral lichen planus in a subset of patients: A single-center experience |
| title_fullStr | Characterization of oral lichen planus in a subset of patients: A single-center experience |
| title_full_unstemmed | Characterization of oral lichen planus in a subset of patients: A single-center experience |
| title_short | Characterization of oral lichen planus in a subset of patients: A single-center experience |
| title_sort | characterization of oral lichen planus in a subset of patients a single center experience |
| topic | lichen planus lichen planus characteristics lichen planus treatment oral lichen planus oral ulcers |
| url | http://www.saudijos.org//article.asp?issn=1658-6816;year=2020;volume=7;issue=3;spage=199;epage=205;aulast=Alhelo |
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