SESN2 Knockdown Increases Betulinic Acid-Induced Radiosensitivity of Hypoxic Breast Cancer Cells

SESN2 Knockdown Increases Betulinic Acid-Induced Radiosensitivity of Hypoxic Breast Cancer Cells

Betulinic acid (BA) is a natural compound well known for its anti-inflammatory, anti-viral, anti-bacterial, anti-malarial effects and anti-tumor properties. Its enhanced cytotoxicity in tumor cells and induction of cell death in various cancer entities qualifies BA as an interesting candidate for no...

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Bibliographic Details
Main Authors: Antje Güttler, Claus Weinholdt, Elisabeth Ruff, Judith Reidt, Elisa Darnstaedt, Alicia Wildemann, Marina Petrenko, Jacqueline Keßler, Matthias Kappler, Ivo Grosse, Dirk Vordermark, Matthias Bache
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
betulinic acid
sestrin-2
knockdown
radiosensitivity
autophagy
breast cancer
Online Access:https://www.mdpi.com/2073-4409/12/1/177

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