HIV pre-exposure prophylaxis for women

Women and girls comprise nearly half of HIV-infected individuals globally and 20% of new infections in the United States, indicating an urgent need to optimise HIV prevention options in this population. HIV pre-exposure prophylaxis (PrEP) – where antiretrovirals are administered to HIV-non-infected...

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Main Authors: Anandi N. Sheth, Charlotte P. Rolle, Monica Gandhi
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Journal of Virus Eradication
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020304581
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author Anandi N. Sheth
Charlotte P. Rolle
Monica Gandhi
author_facet Anandi N. Sheth
Charlotte P. Rolle
Monica Gandhi
author_sort Anandi N. Sheth
collection DOAJ
description Women and girls comprise nearly half of HIV-infected individuals globally and 20% of new infections in the United States, indicating an urgent need to optimise HIV prevention options in this population. HIV pre-exposure prophylaxis (PrEP) – where antiretrovirals are administered to HIV-non-infected individuals at risk of HIV acquisition – is a promising, female-controlled HIV prevention strategy but has so far been underutilised in women. Clinical trial data demonstrate efficacy of daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for reduction of HIV acquisition among women when used consistently. Limited HIV risk perception and suboptimal PrEP awareness among women and healthcare personnel are among the challenges with PrEP delivery for women. Future research into the development of new drugs and delivery systems, and integrating PrEP delivery with reproductive healthcare services, provide opportunities to optimise this prevention strategy for women.
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spelling doaj.art-6c62e74386294c25a03c6e8bca22d79e2022-12-21T22:56:05ZengElsevierJournal of Virus Eradication2055-66402016-07-0123149155HIV pre-exposure prophylaxis for womenAnandi N. Sheth0Charlotte P. Rolle1Monica Gandhi2Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine and Grady Health System, Atlanta, GA, USA; Corresponding author: Anandi N Sheth, Department of Medicine, Division of Infectious Diseases, Emory University, 49 Jesse Hill Junior Drive SE, Atlanta, GA, USADepartment of Medicine, Division of Infectious Diseases, Emory University School of Medicine and Grady Health System, Atlanta, GA, USADepartment of Medicine, Division of HIV, Infectious Diseases, and Global Medicine, University of California San Francisco (UCSF), San Francisco, CA, USAWomen and girls comprise nearly half of HIV-infected individuals globally and 20% of new infections in the United States, indicating an urgent need to optimise HIV prevention options in this population. HIV pre-exposure prophylaxis (PrEP) – where antiretrovirals are administered to HIV-non-infected individuals at risk of HIV acquisition – is a promising, female-controlled HIV prevention strategy but has so far been underutilised in women. Clinical trial data demonstrate efficacy of daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for reduction of HIV acquisition among women when used consistently. Limited HIV risk perception and suboptimal PrEP awareness among women and healthcare personnel are among the challenges with PrEP delivery for women. Future research into the development of new drugs and delivery systems, and integrating PrEP delivery with reproductive healthcare services, provide opportunities to optimise this prevention strategy for women.http://www.sciencedirect.com/science/article/pii/S2055664020304581Pre-exposure prophylaxiswomen's healthHIV prevention
spellingShingle Anandi N. Sheth
Charlotte P. Rolle
Monica Gandhi
HIV pre-exposure prophylaxis for women
Journal of Virus Eradication
Pre-exposure prophylaxis
women's health
HIV prevention
title HIV pre-exposure prophylaxis for women
title_full HIV pre-exposure prophylaxis for women
title_fullStr HIV pre-exposure prophylaxis for women
title_full_unstemmed HIV pre-exposure prophylaxis for women
title_short HIV pre-exposure prophylaxis for women
title_sort hiv pre exposure prophylaxis for women
topic Pre-exposure prophylaxis
women's health
HIV prevention
url http://www.sciencedirect.com/science/article/pii/S2055664020304581
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