Role of oral corticosteroid and olfactory training for treatment of Post-COVID-19 olfactory dysfunction: Our experiences
Background: Coronavirus disease 2019 (COVID-19) infection is highly contagious and the increasing number of patients with variety of symptoms. Olfactory loss is currently a well-recognized symptom of COVID-19 infection. Many patients with COVID-19 infections recover with their normal sense of smell...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Apollo Medicine |
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| Online Access: | http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2021;volume=18;issue=3;spage=162;epage=165;aulast=Swain |
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| author | Santosh Kumar Swain Somya Ranjan Pani |
| author_facet | Santosh Kumar Swain Somya Ranjan Pani |
| author_sort | Santosh Kumar Swain |
| collection | DOAJ |
| description | Background: Coronavirus disease 2019 (COVID-19) infection is highly contagious and the increasing number of patients with variety of symptoms. Olfactory loss is currently a well-recognized symptom of COVID-19 infection. Many patients with COVID-19 infections recover with their normal sense of smell after few weeks, however certain portion of them develop long-standing olfactory dysfunction. Objective: The objective is to study the role of oral corticosteroids and olfactory training (OT) as a treatment for olfactory dysfunction in COVID-19 patient. Materials and Methods: This is a prospective and descriptive study on 78 COVID-19 patients who administered oral corticosteroids and OT. All of them were diagnosed with COVID-19 infection by reverse transcription polymerase chain reaction of nasopharyngeal swab. The detail clinical examination and treatment with intranasal corticosteroid and its outcome were analyzed. Results: In this study, 46 (58.97%) patients were male and 32 (41.02%) were female with male to female ratio of 1.43:1. The age ranges of 18–62 years. There were 36 (46.15%) patients in the age range of 18–30 years, 42 (53.84%) patients in the age range of 31–62 years. Out of 78 patients, 11 (14.10%) patients were recovered after 2 weeks, 34 (43.58%) patients recovered after 3 weeks, and 24 (30.76%) recovered after 4 weeks. Three patients lost follow-up during the treatment period. Conclusion: Combination of short course of oral corticosteroids and OT is a beneficial and safe treatment option for COVID-19 patients with olfactory dysfunction. However, there is a crucial demand for further studies to corroborate this outcome. |
| first_indexed | 2024-12-17T22:25:19Z |
| format | Article |
| id | doaj.art-6c6360e5f6fe469dacca537c19e1d156 |
| institution | Directory Open Access Journal |
| issn | 0976-0016 2213-3682 |
| language | English |
| last_indexed | 2024-12-17T22:25:19Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Apollo Medicine |
| spelling | doaj.art-6c6360e5f6fe469dacca537c19e1d1562022-12-21T21:30:21ZengWolters Kluwer Medknow PublicationsApollo Medicine0976-00162213-36822021-01-0118316216510.4103/am.am_61_21Role of oral corticosteroid and olfactory training for treatment of Post-COVID-19 olfactory dysfunction: Our experiencesSantosh Kumar SwainSomya Ranjan PaniBackground: Coronavirus disease 2019 (COVID-19) infection is highly contagious and the increasing number of patients with variety of symptoms. Olfactory loss is currently a well-recognized symptom of COVID-19 infection. Many patients with COVID-19 infections recover with their normal sense of smell after few weeks, however certain portion of them develop long-standing olfactory dysfunction. Objective: The objective is to study the role of oral corticosteroids and olfactory training (OT) as a treatment for olfactory dysfunction in COVID-19 patient. Materials and Methods: This is a prospective and descriptive study on 78 COVID-19 patients who administered oral corticosteroids and OT. All of them were diagnosed with COVID-19 infection by reverse transcription polymerase chain reaction of nasopharyngeal swab. The detail clinical examination and treatment with intranasal corticosteroid and its outcome were analyzed. Results: In this study, 46 (58.97%) patients were male and 32 (41.02%) were female with male to female ratio of 1.43:1. The age ranges of 18–62 years. There were 36 (46.15%) patients in the age range of 18–30 years, 42 (53.84%) patients in the age range of 31–62 years. Out of 78 patients, 11 (14.10%) patients were recovered after 2 weeks, 34 (43.58%) patients recovered after 3 weeks, and 24 (30.76%) recovered after 4 weeks. Three patients lost follow-up during the treatment period. Conclusion: Combination of short course of oral corticosteroids and OT is a beneficial and safe treatment option for COVID-19 patients with olfactory dysfunction. However, there is a crucial demand for further studies to corroborate this outcome.http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2021;volume=18;issue=3;spage=162;epage=165;aulast=Swaincoronavirus disease 2019olfactory dysfunctionolfactory trainingoral corticosteroidsevere acute respiratory syndrome corona virus 2 |
| spellingShingle | Santosh Kumar Swain Somya Ranjan Pani Role of oral corticosteroid and olfactory training for treatment of Post-COVID-19 olfactory dysfunction: Our experiences Apollo Medicine coronavirus disease 2019 olfactory dysfunction olfactory training oral corticosteroid severe acute respiratory syndrome corona virus 2 |
| title | Role of oral corticosteroid and olfactory training for treatment of Post-COVID-19 olfactory dysfunction: Our experiences |
| title_full | Role of oral corticosteroid and olfactory training for treatment of Post-COVID-19 olfactory dysfunction: Our experiences |
| title_fullStr | Role of oral corticosteroid and olfactory training for treatment of Post-COVID-19 olfactory dysfunction: Our experiences |
| title_full_unstemmed | Role of oral corticosteroid and olfactory training for treatment of Post-COVID-19 olfactory dysfunction: Our experiences |
| title_short | Role of oral corticosteroid and olfactory training for treatment of Post-COVID-19 olfactory dysfunction: Our experiences |
| title_sort | role of oral corticosteroid and olfactory training for treatment of post covid 19 olfactory dysfunction our experiences |
| topic | coronavirus disease 2019 olfactory dysfunction olfactory training oral corticosteroid severe acute respiratory syndrome corona virus 2 |
| url | http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2021;volume=18;issue=3;spage=162;epage=165;aulast=Swain |
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