TMBcalc: a computational pipeline for identifying pan-cancer Tumor Mutational Burden gene signatures

TMBcalc: a computational pipeline for identifying pan-cancer Tumor Mutational Burden gene signatures

Background:In the precision medicine era, identifying predictive factors to select patients most likely to benefit from treatment with immunological agents is a crucial and open challenge in oncology.Methods:This paper presents a pan-cancer analysis of Tumor Mutational Burden (TMB). We developed a n...

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Bibliographic Details
Main Authors: Grete Francesca Privitera, Salvatore Alaimo, Anna Caruso, Alfredo Ferro, Stefano Forte, Alfredo Pulvirenti
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Genetics
Subjects:
personalized medicine
Tumor Mutational Burden
DNA-seq
analysis pipeline
pan-cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1285305/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2024.1285305/full

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