Warfarin dose requirement and cytochrome P450 2C9 and Vitamin K epoxide reductase complex subunit 1-1639 genetic polymorphisms in Thai patients

Warfarin dose requirement and cytochrome P450 2C9 and Vitamin K epoxide reductase complex subunit 1-1639 genetic polymorphisms in Thai patients

Aims: The purposes of this study were to investigate the influence of genetic polymorphisms of cytochrome P450 2C9 (CYP2C9)FNx013 and Vitamin K epoxide reductase complex subunit 1-1639 (VKORC1-1639) G >A and patient′s characteristics on warfarin dose requirement and to establish an equation for p...

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Bibliographic Details
Main Authors: Burassakorn Subsuphan, Chatchai Chinpaisal, Manat Pongchaidecha, Wibun Phanthabordeekorn, Surawut Watana
Format: Article
Language:English
Published: Archives of Global Professionals 2016-01-01
Series:Archives of Pharmacy Practice
Subjects:
Cytochrome P450 2C9 isozyme
genetic polymorphism
Vitamin K epoxide reductase complex subunit 1
warfarin
Online Access:http://www.archivepp.com/article.asp?issn=2045-080X;year=2016;volume=7;issue=1;spage=18;epage=25;aulast=Subsuphan

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