Seroprevalence of Cysticercosis among Epileptic Patients Attending Neurological Units in the Urban Area of Abidjan
Cysticercosis is one of the main causes of secondary epilepsy in sub-Saharan Africa. To estimate the seroprevalence of cysticercosis among epileptic patients, we conducted a cross-sectional study of patients attending neurology consultation in Abidjan, Côte d’Ivoire. <b>Methods</b>: Pati...
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MDPI AG
2021-08-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/9/8/1712 |
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| author | Man-Koumba Soumahoro Jihen Melki Berthe Assi Yves Landry Kangah Mamadou Camara Gildas Boris Tazemda-Kuitsouc Mireille Nowakowski Constance Yapo-Ehounoud Thérèse Sonan Jacques Bellalou Ronan Jambou |
| author_facet | Man-Koumba Soumahoro Jihen Melki Berthe Assi Yves Landry Kangah Mamadou Camara Gildas Boris Tazemda-Kuitsouc Mireille Nowakowski Constance Yapo-Ehounoud Thérèse Sonan Jacques Bellalou Ronan Jambou |
| author_sort | Man-Koumba Soumahoro |
| collection | DOAJ |
| description | Cysticercosis is one of the main causes of secondary epilepsy in sub-Saharan Africa. To estimate the seroprevalence of cysticercosis among epileptic patients, we conducted a cross-sectional study of patients attending neurology consultation in Abidjan, Côte d’Ivoire. <b>Methods</b>: Patients’ socio-demographic and lifestyle data were collected as well as blood samples for serological testing using ELISA and Western blot based on IgG antibodies detection. For qualitative variables comparison, Chi<sup>2</sup> or Fisher tests were used; a Student’s t-test was used to compare quantitative variables. A multivariate logistic regression model was fit to identify risks factors. <b>Results</b>: Among 403 epileptic patients included in the study, 55.3% were male; the median age was 16.9 years; 77% lived in Abidjan; 26.5% were workers. Most patients included in the study had tonic-clonic seizures (80%), and 11.2% had focal deficit signs. The seroprevalence of cysticercosis was 6.0%. The risk was higher in patients over 30 years old (aOR = 5.1 (1.3–20.0)) than in patients under 16. The risk was also considerably high in patients who reported epileptics in the family (aOR = 5 (1.7–14.6)). The risk was three-fold less in females than in males. <b>Conclusions</b>: This study highlighted the exposure of epileptic patients to <i>Taenia solium</i> larvae in an urban area. The risk of positive serology was increased with age, male gender, and family history of epilepsy. |
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| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T08:34:12Z |
| publishDate | 2021-08-01 |
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| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-6c68940733534adb979b3de025747b672023-11-22T08:47:45ZengMDPI AGMicroorganisms2076-26072021-08-0198171210.3390/microorganisms9081712Seroprevalence of Cysticercosis among Epileptic Patients Attending Neurological Units in the Urban Area of AbidjanMan-Koumba Soumahoro0Jihen Melki1Berthe Assi2Yves Landry Kangah3Mamadou Camara4Gildas Boris Tazemda-Kuitsouc5Mireille Nowakowski6Constance Yapo-Ehounoud7Thérèse Sonan8Jacques Bellalou9Ronan Jambou10Department of Epidemiology—Clinical Research, Institut Pasteur de Côte d’Ivoire, Abidjan 01 BP 490, Côte d’IvoireDepartment of Parasitology, Institut Pasteur de Côte d’Ivoire, Abidjan 01 BP 490, Côte d’IvoireNeurology Department, Cocody University Hospital, Abidjan 01 BP V 13, Côte d’IvoireDepartment of Epidemiology—Clinical Research, Institut Pasteur de Côte d’Ivoire, Abidjan 01 BP 490, Côte d’IvoireNeurology Unit, Adjamé General Hospital, Abidjan 03 BP 1856, Côte d’IvoireDepartment of Epidemiology—Clinical Research, Institut Pasteur de Côte d’Ivoire, Abidjan 01 BP 490, Côte d’IvoireRecombinant Protein Platform, Institut Pasteur, 75015 Paris, FranceNeurology Department, Cocody University Hospital, Abidjan 01 BP V 13, Côte d’IvoireNeurology Department, Yopougon University Hospital, Abidjan 21 BP 632, Côte d’IvoireRecombinant Protein Platform, Institut Pasteur, 75015 Paris, FranceDepartment of Parasitology, Institut Pasteur de Côte d’Ivoire, Abidjan 01 BP 490, Côte d’IvoireCysticercosis is one of the main causes of secondary epilepsy in sub-Saharan Africa. To estimate the seroprevalence of cysticercosis among epileptic patients, we conducted a cross-sectional study of patients attending neurology consultation in Abidjan, Côte d’Ivoire. <b>Methods</b>: Patients’ socio-demographic and lifestyle data were collected as well as blood samples for serological testing using ELISA and Western blot based on IgG antibodies detection. For qualitative variables comparison, Chi<sup>2</sup> or Fisher tests were used; a Student’s t-test was used to compare quantitative variables. A multivariate logistic regression model was fit to identify risks factors. <b>Results</b>: Among 403 epileptic patients included in the study, 55.3% were male; the median age was 16.9 years; 77% lived in Abidjan; 26.5% were workers. Most patients included in the study had tonic-clonic seizures (80%), and 11.2% had focal deficit signs. The seroprevalence of cysticercosis was 6.0%. The risk was higher in patients over 30 years old (aOR = 5.1 (1.3–20.0)) than in patients under 16. The risk was also considerably high in patients who reported epileptics in the family (aOR = 5 (1.7–14.6)). The risk was three-fold less in females than in males. <b>Conclusions</b>: This study highlighted the exposure of epileptic patients to <i>Taenia solium</i> larvae in an urban area. The risk of positive serology was increased with age, male gender, and family history of epilepsy.https://www.mdpi.com/2076-2607/9/8/1712cysticercosisurban areaepilepsyseroprevalenceCote d’Ivoire |
| spellingShingle | Man-Koumba Soumahoro Jihen Melki Berthe Assi Yves Landry Kangah Mamadou Camara Gildas Boris Tazemda-Kuitsouc Mireille Nowakowski Constance Yapo-Ehounoud Thérèse Sonan Jacques Bellalou Ronan Jambou Seroprevalence of Cysticercosis among Epileptic Patients Attending Neurological Units in the Urban Area of Abidjan Microorganisms cysticercosis urban area epilepsy seroprevalence Cote d’Ivoire |
| title | Seroprevalence of Cysticercosis among Epileptic Patients Attending Neurological Units in the Urban Area of Abidjan |
| title_full | Seroprevalence of Cysticercosis among Epileptic Patients Attending Neurological Units in the Urban Area of Abidjan |
| title_fullStr | Seroprevalence of Cysticercosis among Epileptic Patients Attending Neurological Units in the Urban Area of Abidjan |
| title_full_unstemmed | Seroprevalence of Cysticercosis among Epileptic Patients Attending Neurological Units in the Urban Area of Abidjan |
| title_short | Seroprevalence of Cysticercosis among Epileptic Patients Attending Neurological Units in the Urban Area of Abidjan |
| title_sort | seroprevalence of cysticercosis among epileptic patients attending neurological units in the urban area of abidjan |
| topic | cysticercosis urban area epilepsy seroprevalence Cote d’Ivoire |
| url | https://www.mdpi.com/2076-2607/9/8/1712 |
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