Inhibitor of DNA binding proteins revealed as orchestrators of steady state, stress and malignant hematopoiesis

Inhibitor of DNA binding proteins revealed as orchestrators of steady state, stress and malignant hematopoiesis

Adult mammalian hematopoiesis is a dynamic cellular process that provides a continuous supply of myeloid, lymphoid, erythroid/megakaryocyte cells for host survival. This process is sustained by regulating hematopoietic stem cells (HSCs) quiescence, proliferation and activation under homeostasis and...

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Bibliographic Details
Main Authors: Shweta Singh, Tanmoy Sarkar, Brad Jakubison, Stephen Gadomski, Andrew Spradlin, Kristbjorn O. Gudmundsson, Jonathan R. Keller
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
ID proteins
hematopoiesis
stem cells
quiescence
stress
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.934624/full

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