Altered cortical processing of sensory input in Huntington disease mouse models

Altered cortical processing of sensory input in Huntington disease mouse models

Huntington disease (HD), a hereditary neurodegenerative disorder, manifests as progressively impaired movement and cognition. Although early abnormalities of neuronal activity in striatum are well established in HD models, there are fewer in vivo studies of the cortex. Here, we record local field po...

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Bibliographic Details
Main Authors: Marja D. Sepers, James P. Mackay, Ellen Koch, Dongsheng Xiao, Majid H. Mohajerani, Allen W. Chan, Amy I. Smith-Dijak, Daniel Ramandi, Timothy H. Murphy, Lynn A. Raymond
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Neurobiology of Disease
Subjects:
Cortex
Huntington disease
Mouse model
Electrophysiology
Mesoscopic imaging
In vivo
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122001322

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