Exercise Prevents Enhanced Postoperative Neuroinflammation and Cognitive Decline and Rectifies the Gut Microbiome in a Rat Model of Metabolic Syndrome

Exercise Prevents Enhanced Postoperative Neuroinflammation and Cognitive Decline and Rectifies the Gut Microbiome in a Rat Model of Metabolic Syndrome

IntroductionPostoperative cognitive decline (PCD) can affect in excess of 10% of surgical patients and can be considerably higher with risk factors including advanced age, perioperative infection, and metabolic conditions such as obesity and insulin resistance. To define underlying pathophysiologic...

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Bibliographic Details
Main Authors:	Xiaomei Feng, Yosuke Uchida, Lauren Koch, Steve Britton, Jun Hu, David Lutrin, Mervyn Maze
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-12-01
Series:	Frontiers in Immunology
Subjects:	preoperative exercise postoperative cognitive decline postoperative neuroinflammation microbiome metabolic syndrome
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01768/full

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