Genistein and sex hormone treatment alleviated hepatic fat accumulation and inflammation in orchidectomized rats with nonalcoholic steatohepatitis

Genistein and sex hormone treatment alleviated hepatic fat accumulation and inflammation in orchidectomized rats with nonalcoholic steatohepatitis

Testosterone deficiency has been reported to accelerate nonalcoholic fatty liver disease (NAFLD). However, there are minimal data on the risk of NAFLD in transgender women and the treatment of NAFLD in this population. This study aimed to investigate the treatment effects and the mechanisms of actio...

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Bibliographic Details
Main Authors: Fatist Okrit, Maneerat Chayanupatkul, Natcha Wanpiyarat, Prasong Siriviriyakul, Duangporn Werawatganon
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Genistein
Sex hormones
Nonalcoholic steatohepatitis
Bilateral orchiectomy
High fat and high fructose diet
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024020863

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