Dihydromyricetin ameliorates diet-induced obesity and promotes browning of white adipose tissue by upregulating IRF4/PGC-1α

Dihydromyricetin ameliorates diet-induced obesity and promotes browning of white adipose tissue by upregulating IRF4/PGC-1α

Abstract Background Promoting the browning of white adipose tissue (WAT) is a promising approach for the treatment of obesity and related comorbidities because it increases energy expenditure. In this study, we investigated whether Dihydromyricetin (DHM), a flavonoid component, could ameliorate diet...

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Bibliographic Details
Main Authors: Qingyang Leng, Jianhua Zhou, Chang Li, Yanhong Xu, Lu Liu, Yi Zhu, Ying Yang, Hongli Zhang, Xiaohua Li
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Nutrition & Metabolism
Subjects:
Dihydromyricetin
Obesity
Browning of WAT
PGC-1α
IRF4
Online Access:https://doi.org/10.1186/s12986-022-00672-6

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