Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection
<p>Abstract</p> <p>Hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection is not uncommon as a result of similar routes of infection. Patients who are coinfected represent a unique group with diverse serologic profiles. Combined chronic hepatitis B and C leads to more seve...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2005-09-01
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| Series: | Annals of Clinical Microbiology and Antimicrobials |
| Subjects: | |
| Online Access: | http://www.ann-clinmicrob.com/content/4/1/13 |
| _version_ | 1818645588739096576 |
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| author | Keeffe Emmet B Crockett Seth D |
| author_facet | Keeffe Emmet B Crockett Seth D |
| author_sort | Keeffe Emmet B |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection is not uncommon as a result of similar routes of infection. Patients who are coinfected represent a unique group with diverse serologic profiles. Combined chronic hepatitis B and C leads to more severe liver disease and an increased risk of hepatocellular carcinoma. Furthermore, coinfected patients represent a treatment challenge. No standard recommendations exist for treatment of viral hepatitis due to dual HBV/HCV infection, and therefore treatment must be individualized based on patient variables such as serologic and virologic profiles, patient's prior exposure to antiviral treatment, and the presence of other parenterally transmitted viruses such as hepatitis D virus and human immunodeficiency virus. The natural history and treatment of patients with HBV and HCV coinfection is reviewed.</p> |
| first_indexed | 2024-12-17T00:33:08Z |
| format | Article |
| id | doaj.art-6c803abc66174ee9983d66a8b10dd3ef |
| institution | Directory Open Access Journal |
| issn | 1476-0711 |
| language | English |
| last_indexed | 2024-12-17T00:33:08Z |
| publishDate | 2005-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Annals of Clinical Microbiology and Antimicrobials |
| spelling | doaj.art-6c803abc66174ee9983d66a8b10dd3ef2022-12-21T22:10:13ZengBMCAnnals of Clinical Microbiology and Antimicrobials1476-07112005-09-01411310.1186/1476-0711-4-13Natural history and treatment of hepatitis B virus and hepatitis C virus coinfectionKeeffe Emmet BCrockett Seth D<p>Abstract</p> <p>Hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection is not uncommon as a result of similar routes of infection. Patients who are coinfected represent a unique group with diverse serologic profiles. Combined chronic hepatitis B and C leads to more severe liver disease and an increased risk of hepatocellular carcinoma. Furthermore, coinfected patients represent a treatment challenge. No standard recommendations exist for treatment of viral hepatitis due to dual HBV/HCV infection, and therefore treatment must be individualized based on patient variables such as serologic and virologic profiles, patient's prior exposure to antiviral treatment, and the presence of other parenterally transmitted viruses such as hepatitis D virus and human immunodeficiency virus. The natural history and treatment of patients with HBV and HCV coinfection is reviewed.</p>http://www.ann-clinmicrob.com/content/4/1/13TreatmentHepatitis BHepatitis CHBV/HCVCoinfectionDual infectionInterferonRibavirinLamivudineTriple infectionHBV/HCV/HDVHBV/HCV/HIV |
| spellingShingle | Keeffe Emmet B Crockett Seth D Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection Annals of Clinical Microbiology and Antimicrobials Treatment Hepatitis B Hepatitis C HBV/HCV Coinfection Dual infection Interferon Ribavirin Lamivudine Triple infection HBV/HCV/HDV HBV/HCV/HIV |
| title | Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection |
| title_full | Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection |
| title_fullStr | Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection |
| title_full_unstemmed | Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection |
| title_short | Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection |
| title_sort | natural history and treatment of hepatitis b virus and hepatitis c virus coinfection |
| topic | Treatment Hepatitis B Hepatitis C HBV/HCV Coinfection Dual infection Interferon Ribavirin Lamivudine Triple infection HBV/HCV/HDV HBV/HCV/HIV |
| url | http://www.ann-clinmicrob.com/content/4/1/13 |
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