Ex vivo stretch reveals altered mechanical properties of isolated dystrophin-deficient hearts.
Duchenne muscular dystrophy (DMD) is a progressive and fatal disease of muscle wasting caused by loss of the cytoskeletal protein dystrophin. In the heart, DMD results in progressive cardiomyopathy and dilation of the left ventricle through mechanisms that are not fully understood. Previous reports...
Main Authors: | Matthew S Barnabei, Joseph M Metzger |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22427904/pdf/?tool=EBI |
Similar Items
-
Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin‐Deficient Hearts
by: David W. Hammers, et al.
Published: (2016-08-01) -
Juvenile cardiomyopathy with dystrophin deficiency
by: Yuhui Luo, et al.
Published: (2024-05-01) -
Dystrophin Deficiency Causes Progressive Depletion of Cardiovascular Progenitor Cells in the Heart
by: Sarka Jelinkova, et al.
Published: (2021-05-01) -
Effects of Mini-Dystrophin on Dystrophin-Deficient, Human Skeletal Muscle-Derived Cells
by: Jinhong Meng, et al.
Published: (2020-09-01) -
Characterization of brain dystrophins absence and impact in dystrophin-deficient Dmdmdx rat model.
by: Dorian Caudal, et al.
Published: (2020-01-01)