The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors
In the rapidly evolving field of interventional oncology, minimally invasive methods, including CT-guided cryoablation, play an increasingly important role in tumor treatment, notably in bone and soft tissue cancers. Cryoablation works using compressed gas-filled probes to freeze tumor cells to temp...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/30/7/495 |
| _version_ | 1797589661765337088 |
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| author | Nicolas Papalexis Leonor Garbin Savarese Giuliano Peta Costantino Errani Gianmarco Tuzzato Paolo Spinnato Federico Ponti Marco Miceli Giancarlo Facchini |
| author_facet | Nicolas Papalexis Leonor Garbin Savarese Giuliano Peta Costantino Errani Gianmarco Tuzzato Paolo Spinnato Federico Ponti Marco Miceli Giancarlo Facchini |
| author_sort | Nicolas Papalexis |
| collection | DOAJ |
| description | In the rapidly evolving field of interventional oncology, minimally invasive methods, including CT-guided cryoablation, play an increasingly important role in tumor treatment, notably in bone and soft tissue cancers. Cryoablation works using compressed gas-filled probes to freeze tumor cells to temperatures below −20 °C, exploiting the Joule–Thompson effect. This cooling causes cell destruction by forming intracellular ice crystals and disrupting blood flow through endothelial cell damage, leading to local ischemia and devascularization. Coupling this with CT technology enables precise tumor targeting, preserving healthy surrounding tissues and decreasing postoperative complications. This review reports the most important literature on CT-guided cryoablation’s application in musculoskeletal oncology, including sarcoma, bone metastases, and bone and soft tissue benign primary tumors, reporting on the success rate, recurrence rate, complications, and technical aspects to maximize success for cryoablation in the musculoskeletal system. |
| first_indexed | 2024-03-11T01:09:42Z |
| format | Article |
| id | doaj.art-6c871cdbce224dfaa0ae45dae8163bec |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-11T01:09:42Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-6c871cdbce224dfaa0ae45dae8163bec2023-11-18T18:56:04ZengMDPI AGCurrent Oncology1198-00521718-77292023-07-013076744677010.3390/curroncol30070495The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue TumorsNicolas Papalexis0Leonor Garbin Savarese1Giuliano Peta2Costantino Errani3Gianmarco Tuzzato4Paolo Spinnato5Federico Ponti6Marco Miceli7Giancarlo Facchini8Diagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Medical Imaging, Hematology and Clinical Oncology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Preto 14049-09, BrazilDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyIn the rapidly evolving field of interventional oncology, minimally invasive methods, including CT-guided cryoablation, play an increasingly important role in tumor treatment, notably in bone and soft tissue cancers. Cryoablation works using compressed gas-filled probes to freeze tumor cells to temperatures below −20 °C, exploiting the Joule–Thompson effect. This cooling causes cell destruction by forming intracellular ice crystals and disrupting blood flow through endothelial cell damage, leading to local ischemia and devascularization. Coupling this with CT technology enables precise tumor targeting, preserving healthy surrounding tissues and decreasing postoperative complications. This review reports the most important literature on CT-guided cryoablation’s application in musculoskeletal oncology, including sarcoma, bone metastases, and bone and soft tissue benign primary tumors, reporting on the success rate, recurrence rate, complications, and technical aspects to maximize success for cryoablation in the musculoskeletal system.https://www.mdpi.com/1718-7729/30/7/495interventional radiologymetastatic neoplasmsorthopedic surgerypalliative medicinecryoablation |
| spellingShingle | Nicolas Papalexis Leonor Garbin Savarese Giuliano Peta Costantino Errani Gianmarco Tuzzato Paolo Spinnato Federico Ponti Marco Miceli Giancarlo Facchini The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors Current Oncology interventional radiology metastatic neoplasms orthopedic surgery palliative medicine cryoablation |
| title | The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors |
| title_full | The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors |
| title_fullStr | The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors |
| title_full_unstemmed | The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors |
| title_short | The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors |
| title_sort | new ice age of musculoskeletal intervention role of percutaneous cryoablation in bone and soft tissue tumors |
| topic | interventional radiology metastatic neoplasms orthopedic surgery palliative medicine cryoablation |
| url | https://www.mdpi.com/1718-7729/30/7/495 |
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