Severe Hyperthermia Induces Apoptosis Mediated by Caspases Activation and Suppression of Hsp90-alpha Expression in Osteosarcoma Cells

Severe Hyperthermia Induces Apoptosis Mediated by Caspases Activation and Suppression of Hsp90-alpha Expression in Osteosarcoma Cells

BACKGROUND: Hyperthermia is used as an adjuvant treatment to sensitize cancer cells to subsequent radiotheraphy or chemotherapy. The aim of this study was to study the effect of severe hyperthermia on osteosarcoma cells and its underlying causes. METHODS: Short-term (1 h) severe hyperthermia (45°C)...

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Bibliographic Details
Main Authors: Mohammed Ali Nashiry, Gabriele Ruth Anisah Froemming, Yeap Swee Keong, Aletza Binti Mohd Ismail, Aisha Mohd Din, Alyaa Mahmood Al-Khateeb
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2019-08-01
Series:Indonesian Biomedical Journal
Online Access:https://inabj.org/index.php/ibj/article/view/594

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