Epidemiological and microbiological characteristics of culture-proven acute otitis media in Taiwanese children
Acute otitis media (AOM) is one of the most common diseases in children. Here, we describe the epidemiological and microbiological characteristics of AOM in Taiwanese children over a 10-year period. Methods: We retrospectively enrolled pediatric patients with culture-proven AOM who were treated at M...
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| Format: | Article |
| Language: | English |
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Elsevier
2012-10-01
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| Series: | Journal of the Formosan Medical Association |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664612000691 |
| _version_ | 1811234574387118080 |
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| author | Nan-Chang Chiu Hsin-Yi Lin Chyong-Hsin Hsu Fu-Yuan Huang Kuo-Sheng Lee Hsin Chi |
| author_facet | Nan-Chang Chiu Hsin-Yi Lin Chyong-Hsin Hsu Fu-Yuan Huang Kuo-Sheng Lee Hsin Chi |
| author_sort | Nan-Chang Chiu |
| collection | DOAJ |
| description | Acute otitis media (AOM) is one of the most common diseases in children. Here, we describe the epidemiological and microbiological characteristics of AOM in Taiwanese children over a 10-year period.
Methods: We retrospectively enrolled pediatric patients with culture-proven AOM who were treated at Mackay Memorial Hospital, Taipei between 1999–2008. The data include demographic characteristics, clinical history, and microbiological characteristics.
Results: Six hundred and fourteen patients were included. The male:female ratio was 1.4 (p<0.001). Greater than three-fourths of the patients (476 [77.5%]) were < 5 years of age, and most patients were 1–2 years of age. The most common isolated pathogen was Streptococcus pneumoniae (419 patients [68.2%]), followed by nontypeable Haemophilus influenzae (NTHi; 118 patients [19.2%]). The distributions of age, gender, use of tympanocentesis, history of previous AOM, and use of antibiotic between patients infected with the two pathogens were not significantly different. However, the number of patients with AOM caused by S. pneumoniae, but not NTHi, decreased during the study period (p=0.004). Three hundred and eighty-seven children (63.0%) with AOM developed spontaneous otorrhea. Compared with patients who underwent tympanocentesis, those with spontaneous otorrhea were younger (27.0±16.4 vs. 31.1±15.2 months of age, p=0.004), more likely to have a previous history of AOM (p=0.019), and more likely to receive more antibiotics (p=0.012). The third most common pathogen was S. pyogenes (25 patients [4.1%]). S. pyogenes occurred more often in children > 5 years of age and was associated with spontaneous otorrhea (p<0.001).
Conclusion: S. pneumoniae and NTHi are common causes of culture-confirmed AOM in Taiwanese children. Although S. pyogenes is not as common, it usually causes AOM in children > 5 years of age and is associated with spontaneous otorrhea. |
| first_indexed | 2024-04-12T11:39:45Z |
| format | Article |
| id | doaj.art-6c9162d5df8d4f9fa2f01c63e5310508 |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-04-12T11:39:45Z |
| publishDate | 2012-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-6c9162d5df8d4f9fa2f01c63e53105082022-12-22T03:34:43ZengElsevierJournal of the Formosan Medical Association0929-66462012-10-011111053654110.1016/j.jfma.2011.07.015Epidemiological and microbiological characteristics of culture-proven acute otitis media in Taiwanese childrenNan-Chang Chiu0Hsin-Yi Lin1Chyong-Hsin Hsu2Fu-Yuan Huang3Kuo-Sheng Lee4Hsin Chi5Department of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Otorhinolaryngology, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanAcute otitis media (AOM) is one of the most common diseases in children. Here, we describe the epidemiological and microbiological characteristics of AOM in Taiwanese children over a 10-year period. Methods: We retrospectively enrolled pediatric patients with culture-proven AOM who were treated at Mackay Memorial Hospital, Taipei between 1999–2008. The data include demographic characteristics, clinical history, and microbiological characteristics. Results: Six hundred and fourteen patients were included. The male:female ratio was 1.4 (p<0.001). Greater than three-fourths of the patients (476 [77.5%]) were < 5 years of age, and most patients were 1–2 years of age. The most common isolated pathogen was Streptococcus pneumoniae (419 patients [68.2%]), followed by nontypeable Haemophilus influenzae (NTHi; 118 patients [19.2%]). The distributions of age, gender, use of tympanocentesis, history of previous AOM, and use of antibiotic between patients infected with the two pathogens were not significantly different. However, the number of patients with AOM caused by S. pneumoniae, but not NTHi, decreased during the study period (p=0.004). Three hundred and eighty-seven children (63.0%) with AOM developed spontaneous otorrhea. Compared with patients who underwent tympanocentesis, those with spontaneous otorrhea were younger (27.0±16.4 vs. 31.1±15.2 months of age, p=0.004), more likely to have a previous history of AOM (p=0.019), and more likely to receive more antibiotics (p=0.012). The third most common pathogen was S. pyogenes (25 patients [4.1%]). S. pyogenes occurred more often in children > 5 years of age and was associated with spontaneous otorrhea (p<0.001). Conclusion: S. pneumoniae and NTHi are common causes of culture-confirmed AOM in Taiwanese children. Although S. pyogenes is not as common, it usually causes AOM in children > 5 years of age and is associated with spontaneous otorrhea.http://www.sciencedirect.com/science/article/pii/S0929664612000691acute otitis medianontypeable Haemophilus influenzaeotorrheaStreptococcus pneumoniae |
| spellingShingle | Nan-Chang Chiu Hsin-Yi Lin Chyong-Hsin Hsu Fu-Yuan Huang Kuo-Sheng Lee Hsin Chi Epidemiological and microbiological characteristics of culture-proven acute otitis media in Taiwanese children Journal of the Formosan Medical Association acute otitis media nontypeable Haemophilus influenzae otorrhea Streptococcus pneumoniae |
| title | Epidemiological and microbiological characteristics of culture-proven acute otitis media in Taiwanese children |
| title_full | Epidemiological and microbiological characteristics of culture-proven acute otitis media in Taiwanese children |
| title_fullStr | Epidemiological and microbiological characteristics of culture-proven acute otitis media in Taiwanese children |
| title_full_unstemmed | Epidemiological and microbiological characteristics of culture-proven acute otitis media in Taiwanese children |
| title_short | Epidemiological and microbiological characteristics of culture-proven acute otitis media in Taiwanese children |
| title_sort | epidemiological and microbiological characteristics of culture proven acute otitis media in taiwanese children |
| topic | acute otitis media nontypeable Haemophilus influenzae otorrhea Streptococcus pneumoniae |
| url | http://www.sciencedirect.com/science/article/pii/S0929664612000691 |
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