Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018
Objectives: To describe the evolution of the incidence of oral cavity cancers (OCC) among elderly patients in France between 1990 and 2018 and to compare it to the incidence of other cancers sharing the same main risk factors. Material and Methods: The incidence of cancers in mainland France from 19...
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MDPI AG
2023-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/3/1071 |
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| author | Alice Renou Anne-Valérie Guizard Emilien Chabrillac Gautier Defossez Pascale Grosclaude Sophie Deneuve Sébastien Vergez Bénédicte Lapotre-Ledoux Sandrine D Plouvier Agnès Dupret-Bories FRANCIM Network |
| author_facet | Alice Renou Anne-Valérie Guizard Emilien Chabrillac Gautier Defossez Pascale Grosclaude Sophie Deneuve Sébastien Vergez Bénédicte Lapotre-Ledoux Sandrine D Plouvier Agnès Dupret-Bories FRANCIM Network |
| author_sort | Alice Renou |
| collection | DOAJ |
| description | Objectives: To describe the evolution of the incidence of oral cavity cancers (OCC) among elderly patients in France between 1990 and 2018 and to compare it to the incidence of other cancers sharing the same main risk factors. Material and Methods: The incidence of cancers in mainland France from 1990 to 2018 was estimated from incidence data observed in every cancer registry of the Francim network. Incidence was modeled by a 2-dimensional penalized spline of age and year of diagnosis, associated with a random effect corresponding to the registry. The elderly population was divided into two groups: 70–79 years old and ≥80 years old. Results: There was a 72% increase in the number of OCC cases in women over 70 years of age between the periods 1990–1999 and 2010–2018. As for men, there was a stabilization in the number of cases (+2%). Over the same period, for laryngeal and hypopharyngeal cancers, there was a decrease in incidence in elderly men and an increase in elderly women, although less marked than for OCC. Conclusions: Since the 1990s, the incidence of OCC has been increasing in elderly subjects in France, particularly in women. Population aging and growth or alcohol and tobacco consumption alone do not seem to explain this increase, which is not observed in the same proportions for other upper aerodigestive tract cancer subsites sharing the same main risk factors. |
| first_indexed | 2024-03-11T09:37:58Z |
| format | Article |
| id | doaj.art-6c93171db6674e2e9c735d0406c039ee |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T09:37:58Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-6c93171db6674e2e9c735d0406c039ee2023-11-16T17:11:21ZengMDPI AGJournal of Clinical Medicine2077-03832023-01-01123107110.3390/jcm12031071Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018Alice Renou0Anne-Valérie Guizard1Emilien Chabrillac2Gautier Defossez3Pascale Grosclaude4Sophie Deneuve5Sébastien Vergez6Bénédicte Lapotre-Ledoux7Sandrine D Plouvier8Agnès Dupret-Bories9FRANCIM NetworkDepartment of Surgery, University Cancer Institute Toulouse—Oncopole, Hôpitaux Universitaires de Toulouse, 31009 Toulouse, FranceFrench Network of Cancer Registries, 31073 Toulouse, FranceDepartment of Surgery, Institut Claudius Regaud, University Cancer Institute Toulouse—Oncopole, 31009 Toulouse, FranceFrench Network of Cancer Registries, 31073 Toulouse, FranceFrench Network of Cancer Registries, 31073 Toulouse, FranceDepartment of ENT, Rouen University Hospital, 76000 Rouen, FranceDepartment of Surgery, University Cancer Institute Toulouse—Oncopole, Hôpitaux Universitaires de Toulouse, 31009 Toulouse, FranceFrench Network of Cancer Registries, 31073 Toulouse, FranceFrench Network of Cancer Registries, 31073 Toulouse, FranceDepartment of Surgery, University Cancer Institute Toulouse—Oncopole, Hôpitaux Universitaires de Toulouse, 31009 Toulouse, FranceObjectives: To describe the evolution of the incidence of oral cavity cancers (OCC) among elderly patients in France between 1990 and 2018 and to compare it to the incidence of other cancers sharing the same main risk factors. Material and Methods: The incidence of cancers in mainland France from 1990 to 2018 was estimated from incidence data observed in every cancer registry of the Francim network. Incidence was modeled by a 2-dimensional penalized spline of age and year of diagnosis, associated with a random effect corresponding to the registry. The elderly population was divided into two groups: 70–79 years old and ≥80 years old. Results: There was a 72% increase in the number of OCC cases in women over 70 years of age between the periods 1990–1999 and 2010–2018. As for men, there was a stabilization in the number of cases (+2%). Over the same period, for laryngeal and hypopharyngeal cancers, there was a decrease in incidence in elderly men and an increase in elderly women, although less marked than for OCC. Conclusions: Since the 1990s, the incidence of OCC has been increasing in elderly subjects in France, particularly in women. Population aging and growth or alcohol and tobacco consumption alone do not seem to explain this increase, which is not observed in the same proportions for other upper aerodigestive tract cancer subsites sharing the same main risk factors.https://www.mdpi.com/2077-0383/12/3/1071elderlyepidemiologyincidenceoral cavity cancer |
| spellingShingle | Alice Renou Anne-Valérie Guizard Emilien Chabrillac Gautier Defossez Pascale Grosclaude Sophie Deneuve Sébastien Vergez Bénédicte Lapotre-Ledoux Sandrine D Plouvier Agnès Dupret-Bories FRANCIM Network Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018 Journal of Clinical Medicine elderly epidemiology incidence oral cavity cancer |
| title | Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018 |
| title_full | Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018 |
| title_fullStr | Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018 |
| title_full_unstemmed | Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018 |
| title_short | Evolution of the Incidence of Oral Cavity Cancers in the Elderly from 1990 to 2018 |
| title_sort | evolution of the incidence of oral cavity cancers in the elderly from 1990 to 2018 |
| topic | elderly epidemiology incidence oral cavity cancer |
| url | https://www.mdpi.com/2077-0383/12/3/1071 |
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