Interactions between HIV-1 reverse transcriptase and the downstream template strand in stable complexes with primer-template.

Interactions between HIV-1 reverse transcriptase and the downstream template strand in stable complexes with primer-template.

Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) forms stable ternary complexes in which RT is bound tightly at fixed positions on the primer-template (P/T). We have probed downstream interactions between RT and the template strand in the complex containing the incoming dNTP (+1...

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Bibliographic Details
Main Authors: Wiriya Rutvisuttinunt, Peter R Meyer, Walter A Scott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2570493?pdf=render

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