A case of polymyalgia rheumatica following influenza B infection

Kentaro Iwata,1 Yasushi Mizuno2 1Division of Infectious Diseases, Kobe University Hospital, 2Department of General Medicine, Kobe City Medical Center General Hospital, Kobe, Japan Abstract: Polymyalgia rheumatica (PMR) is relatively common among the elderly, and is characterized by multiple body ac...

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Main Authors: Iwata K, Mizuno Y
Format: Article
Language:English
Published: Dove Medical Press 2015-10-01
Series:International Journal of General Medicine
Online Access:https://www.dovepress.com/a-case-of-polymyalgia-rheumatica-following-influenza-b-infection-peer-reviewed-article-IJGM
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author Iwata K
Mizuno Y
author_facet Iwata K
Mizuno Y
author_sort Iwata K
collection DOAJ
description Kentaro Iwata,1 Yasushi Mizuno2 1Division of Infectious Diseases, Kobe University Hospital, 2Department of General Medicine, Kobe City Medical Center General Hospital, Kobe, Japan Abstract: Polymyalgia rheumatica (PMR) is relatively common among the elderly, and is characterized by multiple body aches with an elevated erythrocyte sedimentation rate. Even though the etiology of PMR remains unknown, a number of infectious agents have been suggested to cause PMR. Also, there are reports of PMR after influenza vaccination. The exact role of influenza vaccination on the development of PMR remains unknown, but may be associated with specific human leukocyte antigens (HLAs), such as HLA-DRB1 and HLA-DQB1. Whether postvaccination PMR is caused by influenza virus antigen or adjuvants in the vaccine is another unanswered question. We herein report a case of an 85-year-old woman who developed PMR shortly after contracting influenza virus B. Even though infections are hypothesized to be one of the causes of PMR, this is the first-ever case of PMR following influenza virus infection. Further studies may elucidate the exact role of influenza virus infection on the etiology and pathogenesis of PMR. Keywords: polymyalgia rheumatica, influenza, etiology
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spelling doaj.art-6c934a13ac14468aa97db60a55ba27f72022-12-22T03:58:41ZengDove Medical PressInternational Journal of General Medicine1178-70742015-10-012015default34534724246A case of polymyalgia rheumatica following influenza B infectionIwata KMizuno YKentaro Iwata,1 Yasushi Mizuno2 1Division of Infectious Diseases, Kobe University Hospital, 2Department of General Medicine, Kobe City Medical Center General Hospital, Kobe, Japan Abstract: Polymyalgia rheumatica (PMR) is relatively common among the elderly, and is characterized by multiple body aches with an elevated erythrocyte sedimentation rate. Even though the etiology of PMR remains unknown, a number of infectious agents have been suggested to cause PMR. Also, there are reports of PMR after influenza vaccination. The exact role of influenza vaccination on the development of PMR remains unknown, but may be associated with specific human leukocyte antigens (HLAs), such as HLA-DRB1 and HLA-DQB1. Whether postvaccination PMR is caused by influenza virus antigen or adjuvants in the vaccine is another unanswered question. We herein report a case of an 85-year-old woman who developed PMR shortly after contracting influenza virus B. Even though infections are hypothesized to be one of the causes of PMR, this is the first-ever case of PMR following influenza virus infection. Further studies may elucidate the exact role of influenza virus infection on the etiology and pathogenesis of PMR. Keywords: polymyalgia rheumatica, influenza, etiologyhttps://www.dovepress.com/a-case-of-polymyalgia-rheumatica-following-influenza-b-infection-peer-reviewed-article-IJGM
spellingShingle Iwata K
Mizuno Y
A case of polymyalgia rheumatica following influenza B infection
International Journal of General Medicine
title A case of polymyalgia rheumatica following influenza B infection
title_full A case of polymyalgia rheumatica following influenza B infection
title_fullStr A case of polymyalgia rheumatica following influenza B infection
title_full_unstemmed A case of polymyalgia rheumatica following influenza B infection
title_short A case of polymyalgia rheumatica following influenza B infection
title_sort case of polymyalgia rheumatica following influenza b infection
url https://www.dovepress.com/a-case-of-polymyalgia-rheumatica-following-influenza-b-infection-peer-reviewed-article-IJGM
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AT mizunoy caseofpolymyalgiarheumaticafollowinginfluenzabinfection