Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics
Cancer is one of the most common causes of death and affects millions of lives every year. In addition to non-infectious carcinogens, infectious agents contribute significantly to increased incidence of several cancers. Several therapeutic techniques have been used for the treatment of such cancers....
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| Format: | Article |
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MDPI AG
2021-01-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1010-660X/57/2/91 |
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| author | Ayushi Rai Saba Noor Syed Ishraque Ahmad Mohamed F. Alajmi Afzal Hussain Hashim Abbas Gulam Mustafa Hasan |
| author_facet | Ayushi Rai Saba Noor Syed Ishraque Ahmad Mohamed F. Alajmi Afzal Hussain Hashim Abbas Gulam Mustafa Hasan |
| author_sort | Ayushi Rai |
| collection | DOAJ |
| description | Cancer is one of the most common causes of death and affects millions of lives every year. In addition to non-infectious carcinogens, infectious agents contribute significantly to increased incidence of several cancers. Several therapeutic techniques have been used for the treatment of such cancers. Recently, nanotechnology has emerged to advance the diagnosis, imaging, and therapeutics of various cancer types. Nanomaterials have multiple advantages over other materials due to their small size and high surface area, which allow retention and controlled drug release to improve the anti-cancer property. Most cancer therapies have been known to damage healthy cells due to poor specificity, which can be avoided by using nanosized particles. Nanomaterials can be combined with various types of biomaterials to make it less toxic and improve its biocompatibility. Based on these properties, several nanomaterials have been developed which possess excellent anti-cancer efficacy potential and improved diagnosis. This review presents the latest update on novel nanomaterials used to improve the diagnostic and therapeutic of pathogen-associated and non-pathogenic cancers. We further highlighted mechanistic insights into their mode of action, improved features, and limitations. |
| first_indexed | 2024-03-12T06:50:11Z |
| format | Article |
| id | doaj.art-6c9a416e18674aec9ee3ad86ec97d3ed |
| institution | Directory Open Access Journal |
| issn | 1010-660X |
| language | English |
| last_indexed | 2024-03-12T06:50:11Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-6c9a416e18674aec9ee3ad86ec97d3ed2023-09-03T00:18:04ZengMDPI AGMedicina1010-660X2021-01-0157919110.3390/medicina57020091Recent Advances and Implication of Bioengineered Nanomaterials in Cancer TheranosticsAyushi Rai0Saba Noor1Syed Ishraque Ahmad2Mohamed F. Alajmi3Afzal Hussain4Hashim Abbas5Gulam Mustafa Hasan6Department of Nanoscience, Central University of Gujarat, Sector 29, Gandhinagar 382030, IndiaCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, IndiaDepartment of Chemistry, Zakir Husain Delhi College, University of Delhi, New Delhi 110002, IndiaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Medicine, Nottingham University Hospitals, NHS Trust, Nottingham NG7 2UH, UKDepartment of Biochemistry, College of Medicine, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi ArabiaCancer is one of the most common causes of death and affects millions of lives every year. In addition to non-infectious carcinogens, infectious agents contribute significantly to increased incidence of several cancers. Several therapeutic techniques have been used for the treatment of such cancers. Recently, nanotechnology has emerged to advance the diagnosis, imaging, and therapeutics of various cancer types. Nanomaterials have multiple advantages over other materials due to their small size and high surface area, which allow retention and controlled drug release to improve the anti-cancer property. Most cancer therapies have been known to damage healthy cells due to poor specificity, which can be avoided by using nanosized particles. Nanomaterials can be combined with various types of biomaterials to make it less toxic and improve its biocompatibility. Based on these properties, several nanomaterials have been developed which possess excellent anti-cancer efficacy potential and improved diagnosis. This review presents the latest update on novel nanomaterials used to improve the diagnostic and therapeutic of pathogen-associated and non-pathogenic cancers. We further highlighted mechanistic insights into their mode of action, improved features, and limitations.https://www.mdpi.com/1010-660X/57/2/91cancer therapyHPV-mediated cervical cancercontrolled drug releaseanti-cancer efficacygold and silver nanoparticlesquantum dots |
| spellingShingle | Ayushi Rai Saba Noor Syed Ishraque Ahmad Mohamed F. Alajmi Afzal Hussain Hashim Abbas Gulam Mustafa Hasan Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics Medicina cancer therapy HPV-mediated cervical cancer controlled drug release anti-cancer efficacy gold and silver nanoparticles quantum dots |
| title | Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics |
| title_full | Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics |
| title_fullStr | Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics |
| title_full_unstemmed | Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics |
| title_short | Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics |
| title_sort | recent advances and implication of bioengineered nanomaterials in cancer theranostics |
| topic | cancer therapy HPV-mediated cervical cancer controlled drug release anti-cancer efficacy gold and silver nanoparticles quantum dots |
| url | https://www.mdpi.com/1010-660X/57/2/91 |
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