Particular electrocardiographic phenotypes in acute coronary syndromes

Despite continuous efforts in early recognition and timely management, acute coronary syndromes (ACS) continue to be the most common cause of death worldwide. The electrocardiogram (ECG) is the fastest, repeatable and most accesible instrument with diagnostic value, prognostic significance and ther...

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Main Authors: Anamaria Avram, Radu Brezeanu, Alexandru Iancu, Valentin Chioncel, Catalina Andrei, Crina Sinescu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2020-03-01
Series:Romanian Medical Journal
Subjects:
Online Access:https://rmj.com.ro/articles/2020.1/RMJ_2020_1_Art-03.pdf
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author Anamaria Avram
Radu Brezeanu
Alexandru Iancu
Valentin Chioncel
Catalina Andrei
Crina Sinescu
author_facet Anamaria Avram
Radu Brezeanu
Alexandru Iancu
Valentin Chioncel
Catalina Andrei
Crina Sinescu
author_sort Anamaria Avram
collection DOAJ
description Despite continuous efforts in early recognition and timely management, acute coronary syndromes (ACS) continue to be the most common cause of death worldwide. The electrocardiogram (ECG) is the fastest, repeatable and most accesible instrument with diagnostic value, prognostic significance and therapeutic implications. Based on the ECG, ACS are divided into ST segment elevation myocardial infarction (STEMI) and non-ST segment elevation ACS (NSTEACS). Current guidelines recommend emergency reperfusion theraphy only in patients with STEMI. Conventional criteria for the diagnosis of STEMI exclude the patients with atypical ECG findings, correlated with an increased risk of transmural myocardial infarction and considered STEMI equivalents. These particular ECG phenotypes are: new or presumably new bundle branch block, ST segment elevation in aVR, isolated posterior myocardial infarction, de Winter T waves, Wellens syndrome and ischaemia induced Brugada phenocopy. Rapid risk stratification in patients with NSTEACS is crucial for adequate management. The particular ECG phenotypes discussed herein proove the need to redefine the signs of the present or iminent coronary artery occlusion, especially the left anterior descending (LAD) artery, because many patient may benefit from early invasive treatment instead of conservative pharmacological treatment.
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spelling doaj.art-6c9a4446f73c48f9ab0c760fc7b36f132024-02-02T11:40:55ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2020-03-01671142210.37897/RMJ.2020.1.3Particular electrocardiographic phenotypes in acute coronary syndromesAnamaria Avram0Radu Brezeanu1Alexandru Iancu2Valentin Chioncel3Catalina Andrei4Crina Sinescu5“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Bagdasar-Arseni” Emergency Clinical Hospital, Bucharest, Romania “Bagdasar-Arseni” Emergency Clinical Hospital, Bucharest, Romania“Bagdasar-Arseni” Emergency Clinical Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Bagdasar-Arseni” Emergency Clinical Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Bagdasar-Arseni” Emergency Clinical Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Bagdasar-Arseni” Emergency Clinical Hospital, Bucharest, RomaniaDespite continuous efforts in early recognition and timely management, acute coronary syndromes (ACS) continue to be the most common cause of death worldwide. The electrocardiogram (ECG) is the fastest, repeatable and most accesible instrument with diagnostic value, prognostic significance and therapeutic implications. Based on the ECG, ACS are divided into ST segment elevation myocardial infarction (STEMI) and non-ST segment elevation ACS (NSTEACS). Current guidelines recommend emergency reperfusion theraphy only in patients with STEMI. Conventional criteria for the diagnosis of STEMI exclude the patients with atypical ECG findings, correlated with an increased risk of transmural myocardial infarction and considered STEMI equivalents. These particular ECG phenotypes are: new or presumably new bundle branch block, ST segment elevation in aVR, isolated posterior myocardial infarction, de Winter T waves, Wellens syndrome and ischaemia induced Brugada phenocopy. Rapid risk stratification in patients with NSTEACS is crucial for adequate management. The particular ECG phenotypes discussed herein proove the need to redefine the signs of the present or iminent coronary artery occlusion, especially the left anterior descending (LAD) artery, because many patient may benefit from early invasive treatment instead of conservative pharmacological treatment.https://rmj.com.ro/articles/2020.1/RMJ_2020_1_Art-03.pdfacute coronary syndromesrisk stratificationemergency reperfusion theraphystemi equivalents
spellingShingle Anamaria Avram
Radu Brezeanu
Alexandru Iancu
Valentin Chioncel
Catalina Andrei
Crina Sinescu
Particular electrocardiographic phenotypes in acute coronary syndromes
Romanian Medical Journal
acute coronary syndromes
risk stratification
emergency reperfusion theraphy
stemi equivalents
title Particular electrocardiographic phenotypes in acute coronary syndromes
title_full Particular electrocardiographic phenotypes in acute coronary syndromes
title_fullStr Particular electrocardiographic phenotypes in acute coronary syndromes
title_full_unstemmed Particular electrocardiographic phenotypes in acute coronary syndromes
title_short Particular electrocardiographic phenotypes in acute coronary syndromes
title_sort particular electrocardiographic phenotypes in acute coronary syndromes
topic acute coronary syndromes
risk stratification
emergency reperfusion theraphy
stemi equivalents
url https://rmj.com.ro/articles/2020.1/RMJ_2020_1_Art-03.pdf
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