E. adenophorum Induces Cell Cycle and Apoptosis of Renal Cells through Mitochondrial Pathway and Caspase Activation in Saanen Goat.

E. adenophorum Induces Cell Cycle and Apoptosis of Renal Cells through Mitochondrial Pathway and Caspase Activation in Saanen Goat.

The cytotoxicity effects of E. adenophorum on cell cycle and apoptosis of renal cells in Saanen goat was evaluated by TUNEL, DAPI, AO/EB staining, DNA fragmentation assay, Caspase activity, Western-blot, qRT-PCR and flow cytometry analysis. 16 saanen goats randomly divided into four groups were fed...

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Bibliographic Details
Main Authors: Yajun He, Weihong Chen, Yanchun Hu, Biao Luo, Lei Wu, Yan Qiao, Quan Mo, Ruiguang Xu, Yancheng Zhou, Zhihua Ren, Zhicai Zuo, Junliang Deng, Guangneng Peng, Wei He, Yahui Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4575129?pdf=render

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