Demineralized dentin matrix scaffolds for alveolar bone engineering

From the point of view of implant dentistry, this review discusses the development and clinical use of demineralized dentin matrix (DDM) scaffolds, produced from the patient's own extracted teeth, to repair alveolar bone defects. The structure and the organic and inorganic components of DDM are...

Full description

Bibliographic Details
Main Authors: In-Woong Um, Young-Kyun Kim, Masaharu Mitsugi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:The Journal of Indian Prosthodontic Society
Subjects:
Online Access:http://www.j-ips.org/article.asp?issn=0972-4052;year=2017;volume=17;issue=2;spage=120;epage=127;aulast=Um
Description
Summary:From the point of view of implant dentistry, this review discusses the development and clinical use of demineralized dentin matrix (DDM) scaffolds, produced from the patient's own extracted teeth, to repair alveolar bone defects. The structure and the organic and inorganic components of DDM are presented to emphasize the similarities with autogenous bone. Studies of DDM properties, such as osteoinductive and osteoconductive functions as well as efficacy and safety, which are mandatory for its use as a bone graft substitute, are also presented. The clinical applications of powder, block, and moldable DDM are discussed, along with future developments that can support growth factor and stem cell delivery.
ISSN:0972-4052
1998-4057