Demineralized dentin matrix scaffolds for alveolar bone engineering

From the point of view of implant dentistry, this review discusses the development and clinical use of demineralized dentin matrix (DDM) scaffolds, produced from the patient's own extracted teeth, to repair alveolar bone defects. The structure and the organic and inorganic components of DDM are...

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Main Authors: In-Woong Um, Young-Kyun Kim, Masaharu Mitsugi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:The Journal of Indian Prosthodontic Society
Subjects:
Online Access:http://www.j-ips.org/article.asp?issn=0972-4052;year=2017;volume=17;issue=2;spage=120;epage=127;aulast=Um
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author In-Woong Um
Young-Kyun Kim
Masaharu Mitsugi
author_facet In-Woong Um
Young-Kyun Kim
Masaharu Mitsugi
author_sort In-Woong Um
collection DOAJ
description From the point of view of implant dentistry, this review discusses the development and clinical use of demineralized dentin matrix (DDM) scaffolds, produced from the patient's own extracted teeth, to repair alveolar bone defects. The structure and the organic and inorganic components of DDM are presented to emphasize the similarities with autogenous bone. Studies of DDM properties, such as osteoinductive and osteoconductive functions as well as efficacy and safety, which are mandatory for its use as a bone graft substitute, are also presented. The clinical applications of powder, block, and moldable DDM are discussed, along with future developments that can support growth factor and stem cell delivery.
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spelling doaj.art-6c9dcdbfbbe74ed2abc1741b023b0e1a2022-12-21T19:03:01ZengWolters Kluwer Medknow PublicationsThe Journal of Indian Prosthodontic Society0972-40521998-40572017-01-0117212012710.4103/jips.jips_62_17Demineralized dentin matrix scaffolds for alveolar bone engineeringIn-Woong UmYoung-Kyun KimMasaharu MitsugiFrom the point of view of implant dentistry, this review discusses the development and clinical use of demineralized dentin matrix (DDM) scaffolds, produced from the patient's own extracted teeth, to repair alveolar bone defects. The structure and the organic and inorganic components of DDM are presented to emphasize the similarities with autogenous bone. Studies of DDM properties, such as osteoinductive and osteoconductive functions as well as efficacy and safety, which are mandatory for its use as a bone graft substitute, are also presented. The clinical applications of powder, block, and moldable DDM are discussed, along with future developments that can support growth factor and stem cell delivery.http://www.j-ips.org/article.asp?issn=0972-4052;year=2017;volume=17;issue=2;spage=120;epage=127;aulast=UmBone graft substitutedemineralized dentin matrixtooth
spellingShingle In-Woong Um
Young-Kyun Kim
Masaharu Mitsugi
Demineralized dentin matrix scaffolds for alveolar bone engineering
The Journal of Indian Prosthodontic Society
Bone graft substitute
demineralized dentin matrix
tooth
title Demineralized dentin matrix scaffolds for alveolar bone engineering
title_full Demineralized dentin matrix scaffolds for alveolar bone engineering
title_fullStr Demineralized dentin matrix scaffolds for alveolar bone engineering
title_full_unstemmed Demineralized dentin matrix scaffolds for alveolar bone engineering
title_short Demineralized dentin matrix scaffolds for alveolar bone engineering
title_sort demineralized dentin matrix scaffolds for alveolar bone engineering
topic Bone graft substitute
demineralized dentin matrix
tooth
url http://www.j-ips.org/article.asp?issn=0972-4052;year=2017;volume=17;issue=2;spage=120;epage=127;aulast=Um
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AT masaharumitsugi demineralizeddentinmatrixscaffoldsforalveolarboneengineering