Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study
BackgroundPrevious reports have demonstrated a bidirectional relationship between depression and diabetes mellitus (DM), accentuating a need for more intensive depression screening in DM patients. There is a relative paucity of data on the mortality of depressed DM patients in Korea.MethodsRetrospec...
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| Format: | Article |
| Language: | English |
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Korean Diabetes Association
2017-08-01
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| Series: | Diabetes & Metabolism Journal |
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| Online Access: | https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-41-296.pdf |
| _version_ | 1811320068231921664 |
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| author | Jong-Hyun Jeong Yoo Hyun Um Seung-Hyun Ko Jong-Heon Park Joong-Yeol Park Kyungdo Han Kyung-Soo Ko |
| author_facet | Jong-Hyun Jeong Yoo Hyun Um Seung-Hyun Ko Jong-Heon Park Joong-Yeol Park Kyungdo Han Kyung-Soo Ko |
| author_sort | Jong-Hyun Jeong |
| collection | DOAJ |
| description | BackgroundPrevious reports have demonstrated a bidirectional relationship between depression and diabetes mellitus (DM), accentuating a need for more intensive depression screening in DM patients. There is a relative paucity of data on the mortality of depressed DM patients in Korea.MethodsRetrospective data from January 2003 to December 2013 were collected for adult type 2 diabetes mellitus (T2DM) patients older than 30 years using the National Health Information database maintained by the Korean National Health Insurance Service (NHIS). Demographic characteristics were analyzed with descriptive statistics, and the annual prevalence of depression was estimated. Mortality rates and hazard ratios for each age group (stratified into six age groups) of patients diagnosed with T2DM in 2003 were estimated using a Cox proportional hazard method, with the Kaplan-Meier cumulative survival curve showing the overall survival rates according to the T2DM status until the given year of 2013.ResultsThe annual prevalence of depression was consistently higher in T2DM group from 2003 to 2013. The mortality hazard ratio was higher in the depressed in all age groups, and the risk was higher in male groups and in younger-aged groups.ConclusionDepression was significantly associated with a high mortality risk in T2DM patients; hence, a more systematic surveillance of T2DM patients to identify risk factors for depression might contribute significantly to reducing mortality risk in this group of patients. |
| first_indexed | 2024-04-13T12:53:04Z |
| format | Article |
| id | doaj.art-6ca60842ee7746faad8dfaa5812f2655 |
| institution | Directory Open Access Journal |
| issn | 2233-6079 2233-6087 |
| language | English |
| last_indexed | 2024-04-13T12:53:04Z |
| publishDate | 2017-08-01 |
| publisher | Korean Diabetes Association |
| record_format | Article |
| series | Diabetes & Metabolism Journal |
| spelling | doaj.art-6ca60842ee7746faad8dfaa5812f26552022-12-22T02:46:08ZengKorean Diabetes AssociationDiabetes & Metabolism Journal2233-60792233-60872017-08-0141429630210.4093/dmj.2017.41.4.296Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort StudyJong-Hyun Jeong0Yoo Hyun Um1Seung-Hyun Ko2Jong-Heon Park3Joong-Yeol Park4Kyungdo Han5Kyung-Soo Ko6Department of Psychiatry, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.Department of Psychiatry, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.Division of Endocrinology & Metabolism, Department of Internal medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.National Health Insurance Service, Wonju, Korea.Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, Korea.Department of Internal Medicine, Cardiovascular and Metabolic Disease Center, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.BackgroundPrevious reports have demonstrated a bidirectional relationship between depression and diabetes mellitus (DM), accentuating a need for more intensive depression screening in DM patients. There is a relative paucity of data on the mortality of depressed DM patients in Korea.MethodsRetrospective data from January 2003 to December 2013 were collected for adult type 2 diabetes mellitus (T2DM) patients older than 30 years using the National Health Information database maintained by the Korean National Health Insurance Service (NHIS). Demographic characteristics were analyzed with descriptive statistics, and the annual prevalence of depression was estimated. Mortality rates and hazard ratios for each age group (stratified into six age groups) of patients diagnosed with T2DM in 2003 were estimated using a Cox proportional hazard method, with the Kaplan-Meier cumulative survival curve showing the overall survival rates according to the T2DM status until the given year of 2013.ResultsThe annual prevalence of depression was consistently higher in T2DM group from 2003 to 2013. The mortality hazard ratio was higher in the depressed in all age groups, and the risk was higher in male groups and in younger-aged groups.ConclusionDepression was significantly associated with a high mortality risk in T2DM patients; hence, a more systematic surveillance of T2DM patients to identify risk factors for depression might contribute significantly to reducing mortality risk in this group of patients.https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-41-296.pdfDepressionDiabetes mellitusMortalityPrognosis |
| spellingShingle | Jong-Hyun Jeong Yoo Hyun Um Seung-Hyun Ko Jong-Heon Park Joong-Yeol Park Kyungdo Han Kyung-Soo Ko Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study Diabetes & Metabolism Journal Depression Diabetes mellitus Mortality Prognosis |
| title | Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study |
| title_full | Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study |
| title_fullStr | Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study |
| title_full_unstemmed | Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study |
| title_short | Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study |
| title_sort | depression and mortality in people with type 2 diabetes mellitus 2003 to 2013 a nationwide population based cohort study |
| topic | Depression Diabetes mellitus Mortality Prognosis |
| url | https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-41-296.pdf |
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